Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/49060
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Type: Journal article
Title: Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury
Author: Burcham, P.
Kaminskas, L.
Tan, D.
Pyke, S.
Citation: Mini-Reviews in Medicinal Chemistry, 2008; 8(4):319-330
Publisher: Bentham Science Publishers Ltd.
Issue Date: 2008
ISSN: 1389-5575
1875-5607
Abstract: This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to “carbonyl stress” during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed.
Keywords: Animals
Humans
Liver Diseases, Alcoholic
Alzheimer Disease
Spinal Cord Injuries
Acrolein
Hydralazine
Free Radical Scavengers
Protective Agents
Cell Death
Oxidative Stress
Atherosclerosis
DOI: 10.2174/138955708783955953
Published version: http://dx.doi.org/10.2174/138955708783955953
Appears in Collections:Aurora harvest 5
Chemistry and Physics publications

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