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https://hdl.handle.net/2440/49060
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Type: | Journal article |
Title: | Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury |
Author: | Burcham, P. Kaminskas, L. Tan, D. Pyke, S. |
Citation: | Mini-Reviews in Medicinal Chemistry, 2008; 8(4):319-330 |
Publisher: | Bentham Science Publishers Ltd. |
Issue Date: | 2008 |
ISSN: | 1389-5575 1875-5607 |
Abstract: | This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to “carbonyl stress” during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed. |
Keywords: | Animals Humans Liver Diseases, Alcoholic Alzheimer Disease Spinal Cord Injuries Acrolein Hydralazine Free Radical Scavengers Protective Agents Cell Death Oxidative Stress Atherosclerosis |
DOI: | 10.2174/138955708783955953 |
Published version: | http://dx.doi.org/10.2174/138955708783955953 |
Appears in Collections: | Aurora harvest 5 Chemistry and Physics publications |
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