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|Title:||Carbonyl-scavenging drugs & protection against carbonyl stress-associated cell injury|
|Citation:||Mini - Reviews in Medicinal Chemistry, 2008; 8(4):319-330|
|Publisher:||Bentham Science Publishers Ltd.|
|Abstract:||This mini-review highlights the chemical and cytoprotective properties of various hydralazine analogues that block the induction of cell death by acrolein, a highly toxic contributor to “carbonyl stress” during a diverse range of human diseases. Recent work on the action of hydralazine against various carbonyl-mediated pathologies is also reviewed.|
|Keywords:||Animals; Humans; Liver Diseases, Alcoholic; Alzheimer Disease; Spinal Cord Injuries; Acrolein; Hydralazine; Free Radical Scavengers; Protective Agents; Cell Death; Oxidative Stress; Atherosclerosis|
|Appears in Collections:||Chemistry and Physics publications|
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