Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/49926
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Type: Journal article
Title: The prediction of transmitted dose distributions using a 3D treatment planning system
Author: Reich, P.
Bezak, E.
Mohammadi, M.
Fog, L.
Citation: Australasian Physical and Engineering Sciences in Medicine, 2006; 29(1):18-29
Publisher: Australasian College of Physical Scientists and Engineers in Medicine
Issue Date: 2006
ISSN: 0158-9938
1879-5447
Statement of
Responsibility: 
P. Reich, E. Bezak, M. Mohammadi and L. Fog
Abstract: Patient dose verification is becoming increasingly important with the advent of new complex radiotherapy techniques such as conformal radiotherapy (CRT) and intensity-modulated radiotherapy (IMRT). An electronic portal imaging device (EPID) has potential application for in vivo dosimetry. In the current work, an EPID has been modelled using a treatment planning system (TPS) to predict transmitted dose maps. A thin slab of RW3 material used to initially represent the EPID. A homogeneous RW3 phantom and the thin RW3 slab placed at a clinical distance away from the phantom were scanned using a CT simulator. The resulting CT images were transferred via DICOM to the TPS and the density of the CT data corresponding to the thin RW3 slab was changed to 1 g/cm3. Transmitted dose maps (TDMs) in the modelled EPID were calculated by the TPS using the collapsed-cone (C-C) convolution superposition (C/S) algorithm. A 6 MV beam was used in the simulation to deliver 300 MU to the homogenous phantom using an isocentric and SSD (source-to-surface) technique. The phantom thickness was varied and the calculated TDMs in the modelled EPID were compared with corresponding measurements obtained from a calibrated scanning liquid-filled ionisation chamber (SLIC) EPID. The two TDMs were compared using the gamma evaluation technique of Low et al. The predicted and measured TDMs agree to within 2 % (averaged over all phantom thicknesses) on the central beam axis. More than 90 % of points in the dose maps (excluding field edges) produce a gamma index less than or equal to 1, for dose difference (averaged over all phantom thicknesses), and distance-to-agreement criteria of 4 %, 3.8 mm, respectively. In addition, the noise level on the central axis in the predicted dose maps is less than 0.1 %. We found that phantom thickness changes of approximately 1 mm, which correspond to dose changes on the central beam axis of less than 0.6 %, can be detected in the predicted transmitted dose distributions.
Keywords: Humans
Neoplasms
Radiographic Image Interpretation, Computer-Assisted
Imaging, Three-Dimensional
Subtraction Technique
Radiotherapy, Conformal
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Sensitivity and Specificity
Reproducibility of Results
Radiometry
Body Burden
Phantoms, Imaging
Relative Biological Effectiveness
Algorithms
Scattering, Radiation
Models, Biological
Computer Simulation
DOI: 10.1007/BF03178824
Appears in Collections:Aurora harvest
Chemistry and Physics publications

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