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Type: Journal article
Title: The effect of CPP-ACP on enamel wear under severe erosive conditions
Author: Ranjitkar, S.
Kaidonis, J.
Richards, L.
Townsend, G.
Citation: Archives of Oral Biology, 2009; 54(6):527-532
Publisher: Pergamon-Elsevier Science Ltd
Issue Date: 2009
ISSN: 0003-9969
Statement of
Sarbin Ranjitkar, John A. Kaidonis, Lindsay C. Richards and Grant C. Townsend
Abstract: <h4>Objective</h4>In addition to its role as a remineralizing agent in preventing dental caries, recent evidence has shown that casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) can protect teeth against erosion. The aim of this study was to determine whether CPP-ACP could reduce enamel wear rates under severe erosive conditions simulating heavy attrition and gastric regurgitation.<h4>Design</h4>Enamel specimens were subjected to 10,000 wear cycles at a load of 100 N and pH 1.2 in a tooth wear machine. The machine was stopped every 2 min (160 cycles), and CPP-ACP in the form of a paste was applied for 5 min in experimental group 1. A paste with the same formulation but without CPP-ACP was applied in experimental group 2. No paste was applied in the control group.<h4>Results</h4>A linear mixed model analysis indicated that the mean wear rates in experimental group 1 (0.44+/-0.05 mm(3) per 1000 cycles) and in experimental group 2 (0.63+/-0.06 mm(3) per 1000 cycles) were significantly lower than that in the control group (0.92+/-0.11 mm(3) per 1000 cycles) (p<0.05). The mean wear rate in experimental group 1 was also lower than that in experimental group 2 (p<0.05). Wear facets in experimental groups 1 and 2 were noted to be smoother and more polished than those in the control group.<h4>Conclusions</h4>Both remineralizing and lubricating properties of the paste containing CPP-ACP appear to contribute to wear reduction in enamel. These findings may lead to new strategies for the clinical management of tooth wear.
Keywords: Dental Enamel
Tooth Attrition
Tooth Erosion
Hydrochloric Acid
Cariostatic Agents
Materials Testing
Hydrogen-Ion Concentration
Time Factors
Description: Copyright © 2009 Elsevier Ltd All rights reserved.
DOI: 10.1016/j.archoralbio.2009.03.006
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Dentistry publications

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