Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Relationship between symptoms and dietary patterns in patients with functional dyspepsia
Author: Pilichiewicz, A.
Horowitz, M.
Holtmann, G.
Talley, N.
Feinle-Bisset, C.
Citation: Clinical Gastroenterology and Hepatology, 2009; 7(3):317-322
Publisher: W. B. Saunders & Co.
Issue Date: 2009
ISSN: 1542-3565
Statement of
Amelia N. Pilichiewicz, Michael Horowitz, Gerald J. Holtmann, Nicholas J. Talley and Christine Feinle–Bisset
Abstract: Background & Aims: Patients with functional dyspepsia (FD) often report that their symptoms are related to food ingestion. However, there is a lack of information about differences in eating patterns and nutrient intake between these patients and healthy individuals or the association with specific symptoms. We performed a prospective trial to evaluate the relationship between FD symptoms and dietary factors. Methods: Twenty patients with FD (17 women) and 21 healthy subjects (18 women) completed detailed diet diaries, recording all foods eaten, drinks consumed, and times of consumption, as well as the occurrence, timing, and severity of dyspeptic symptoms (ie, nausea, discomfort, fullness, bloating, upper-abdominal/epigastric pain) for 7 days. Data from the diet diaries were analyzed for the number of meals, light meals, snacks and drinks, energy intake, and macronutrient distribution. Results: Patients with FD ate fewer meals (P < .01) and consumed less total energy (P = .1) and fat (P = .1) than healthy subjects. Their symptoms were modest in severity (score out of 10; 5 [range, 3–8]) and occurred within 31 minutes (range, 8–64 min) of eating. Fullness was related directly to the amount of fat ingested (z, 1.91; P < .05) and overall energy intake (z, 2.12; P < .05) and related inversely to the amount of carbohydrate ingested (z, −1.9; P = .05). Similarly, bloating was related to the amount of fat ingested (z, 1.68; P = .09). There was no significant relationship between symptom severity and any of the dietary variables measured. Conclusions: Management of patients with FD might be improved by instructing them to consume smaller meals with reduced fat content.
Keywords: Humans
Abdominal Pain
Prospective Studies
Feeding Behavior
Middle Aged
Diet Records
Statistics as Topic
Young Adult
Rights: © 2009 AGA Institute. Published by Elsevier Inc. All rights reserved.
DOI: 10.1016/j.cgh.2008.09.007
Description (link):
Appears in Collections:Aurora harvest 5
Medicine publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.