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Type: Journal article
Title: Use of antireflux medication after antireflux surgery
Author: Wijnhoven, B.
Lally, C.
Kelly, J.
Myers, J.
Watson, D.
Citation: Journal of Gastrointestinal Surgery, 2008; 12(3):510-517
Publisher: Elsevier Svience Inc
Issue Date: 2008
ISSN: 1091-255X
Statement of
Bas P. L. Wijnhoven, Carolyn J. Lally, John J. Kelly, Jennifer C. Myers and David I. Watson
Abstract: Introduction It is claimed that a substantial number of patients who undergo antireflux surgery use antireflux medication postoperatively. This study was aimed to determine the prevalence and underlying reasons for antireflux medication usage in patients after surgery. Materials and Methods A questionnaire on the usage of antireflux medication was sent to 1,008 patients identified from a prospective database of patients who had undergone a laparoscopic antireflux procedure. Results A total of 844 patients (84%) returned the questionnaire. Mean follow-up was 5.9 years after surgery. A single or combination of medications was being taken by 312 patients (37%): 82% proton pump inhibitors, 9% H2-blockers and 34% antacids. Fifty-two patients (17%) had never stopped taking medication, whereas 260 patients (83%) restarted medication at a mean of 2.5 years after surgery. Return of the same (31%) or different (49%) symptoms were the commonest reasons for taking medication, whereas 20% were asymptomatic or had other reasons for medication use. Postoperative 24-hour pH studies were abnormal in 16/61 patients (26%) on medication and in 5/78 patients (6%) not taking medication. Conclusions Antireflux medication is frequently taken by many patients for various symptoms after antireflux surgery. Symptomatic patients should be properly investigated before antireflux medications are prescribed.
Keywords: Medication; Gastroesophageal reflux; Fundoplication
Description: The original publication can be found at
Provenance: Published online: 11 December 2007
RMID: 0020080273
DOI: 10.1007/s11605-007-0443-1
Appears in Collections:Surgery publications

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