Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/51594
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Type: Journal article
Title: Laparoscopic fundoplication in patients with a hypertensive lower esophageal sphincter
Author: Lamb, P.
Myers, J.
Thompson, S.
Jamieson, G.
Citation: Journal of Gastrointestinal Surgery, 2009; 13(1):61-65
Publisher: Elsevier Svience Inc
Issue Date: 2009
ISSN: 1091-255X
1873-4626
Statement of
Responsibility: 
Peter J. Lamb, Jennifer C. Myers, Sarah K. Thompson and Glyn G. Jamieson
Abstract: Background: A small proportion of patients evaluated with manometry prior to a fundoplication have a high-pressure lower esophageal sphincter (LES). This paper examines the outcome of laparoscopic fundoplication for these patients. Material and Methods: Between October 1991 and December 2006, 1,886 patients underwent primary laparoscopic fundoplication. Those with a high-pressure LES on preoperative manometry (LESP ≥30 mm Hg at end expiration) were identified from a prospective database. Long-term outcomes were determined using analogue symptom scores (0–10) for heartburn, dysphagia, and patient satisfaction and compared to those of a matched control group. Results: Thirty patients (1.6%), nine men and 21 women, median age 51 years, had a hypertensive LES (mean, 36 mmHg; range, 30–55). Median: follow-up after fundoplication was 99 (12–182) months. These patients had similar mean symptom scores to 30 matched controls for heartburn (2.3 vs. 2.2, P = 0.541), dysphagia (2.7 vs. 3.1, P = 0.539), and satisfaction (7.4 vs. 7.6, P = 0.546). Five patients required revision for dysphagia compared to no control patients (P = 0.005). These patients had a higher preoperative dysphagia score (6.6 vs. 3.1, P = 0.036). Conclusion: Laparoscopic fundoplication can be performed with good long-term results for patients with reflux and a hypertensive LES. However, those with preoperative dysphagia have a higher failure rate.
Keywords: Lower esophageal sphincter; Antireflux surgery; Gastroesophageal reflux
RMID: 0020083781
DOI: 10.1007/s11605-008-0688-3
Appears in Collections:Surgery publications

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