Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/51975
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Type: Journal article
Title: Reproductive biology in egg-laying mammals
Author: Grutzner, F.
Nixon, B.
Jones, R.
Citation: Sexual Development, 2008; 2(3):115-127
Publisher: S. Karger AG
Issue Date: 2008
ISSN: 1661-5425
1661-5433
Statement of
Responsibility: 
F. Grützner, B. Nixon, R.C. Jones
Abstract: The duck-billed platypus and short-beaked echidna are iconic species in Australia. Their morphology and physiology have puzzled scientists all over the world for more than 200 years. Recent genetic studies, particularly the platypus whole-genome sequencing project, have revealed the molecular basis of some of the extraordinary characteristics of monotremes. This and other works demonstrate the great value of research on our most distantly related mammalian relatives for comparative genomics and developmental biology. In this review we focus on the reproductive biology of monotremes and discuss works that unravel genes involved in lactation, testicular descent, gamete biology and fertilization, and early development. In addition we discuss works on the evolution of the complex sex chromosome system in platypus and echidna, which has also significant impact on our general understanding of mammalian sex chromosomes and sex determination.
Keywords: Development; Echidna; Fertilization; Lactation; Ova; Platypus; Reproduction; Sex chromosomes; Sperm
RMID: 0020082549
DOI: 10.1159/000143429
Appears in Collections:Molecular and Biomedical Science publications
Environment Institute Leaders publications

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