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https://hdl.handle.net/2440/52140
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dc.contributor.author | Wong, A. | - |
dc.contributor.author | Myers, J. | - |
dc.contributor.author | Jamieson, G. | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Journal of Gastrointestinal Surgery, 2008; 12(8):1341-1345 | - |
dc.identifier.issn | 1091-255X | - |
dc.identifier.issn | 1873-4626 | - |
dc.identifier.uri | http://hdl.handle.net/2440/52140 | - |
dc.description | The original publication can be found at www.springerlink.com | - |
dc.description.abstract | In Barrett’s esophagus, total abolition of reflux may give maximum protection against the development of malignancy. To determine whether laparoscopic anterior fundoplication gives the same degree of antireflux control as a total fundoplication, we analyzed a prospectively followed cohort of patients from randomized controlled trials of laparoscopic antireflux surgery. There were 167 patients who returned for routine esophageal pH studies within 6 months of surgery (123 laparoscopic total fundoplications and 44 anterior fundoplications). There was no difference in percentage time pH <4 between fundoplication groups, but the total number of reflux episodes was significantly different (total fundoplication, four reflux events vs. partial fundoplication, six reflux events; p = 0.03). It is difficult to believe that this difference is either biologically or clinically important. In patients with a second esophageal pH study more than 5 years later, both the percentage time pH <4 (0.1% total fundoplication vs. 2.7% partial fundoplication; p = 0.004) and total number of reflux episodes (three total fundoplication vs. 24 partial fundoplication; p = 0.002) were significantly different. However, the postoperative esophageal acid exposure was within the normal range for both total and partial fundoplication, so whether the statistical difference is clinically important, remains a moot point. | - |
dc.description.statementofresponsibility | Andrew S. Y. Wong, Jennifer C. Myers and Glyn G. Jamieson | - |
dc.language.iso | en | - |
dc.publisher | Elsevier Svience Inc | - |
dc.source.uri | http://dx.doi.org/10.1007/s11605-008-0486-y | - |
dc.subject | Laparoscopic fundoplication | - |
dc.subject | Gastro-esophageal reflux | - |
dc.subject | Esophageal pH monitoring | - |
dc.subject | Randomized controlled trial | - |
dc.title | Esophageal pH profile following laparoscopic total fundoplication compared to anterior fundoplication | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1007/s11605-008-0486-y | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Myers, J. [0000-0003-2157-7098] | - |
Appears in Collections: | Aurora harvest 5 Surgery publications |
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