Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/52140
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dc.contributor.authorWong, A.-
dc.contributor.authorMyers, J.-
dc.contributor.authorJamieson, G.-
dc.date.issued2008-
dc.identifier.citationJournal of Gastrointestinal Surgery, 2008; 12(8):1341-1345-
dc.identifier.issn1091-255X-
dc.identifier.issn1873-4626-
dc.identifier.urihttp://hdl.handle.net/2440/52140-
dc.descriptionThe original publication can be found at www.springerlink.com-
dc.description.abstractIn Barrett’s esophagus, total abolition of reflux may give maximum protection against the development of malignancy. To determine whether laparoscopic anterior fundoplication gives the same degree of antireflux control as a total fundoplication, we analyzed a prospectively followed cohort of patients from randomized controlled trials of laparoscopic antireflux surgery. There were 167 patients who returned for routine esophageal pH studies within 6 months of surgery (123 laparoscopic total fundoplications and 44 anterior fundoplications). There was no difference in percentage time pH <4 between fundoplication groups, but the total number of reflux episodes was significantly different (total fundoplication, four reflux events vs. partial fundoplication, six reflux events; p = 0.03). It is difficult to believe that this difference is either biologically or clinically important. In patients with a second esophageal pH study more than 5 years later, both the percentage time pH <4 (0.1% total fundoplication vs. 2.7% partial fundoplication; p = 0.004) and total number of reflux episodes (three total fundoplication vs. 24 partial fundoplication; p = 0.002) were significantly different. However, the postoperative esophageal acid exposure was within the normal range for both total and partial fundoplication, so whether the statistical difference is clinically important, remains a moot point.-
dc.description.statementofresponsibilityAndrew S. Y. Wong, Jennifer C. Myers and Glyn G. Jamieson-
dc.language.isoen-
dc.publisherElsevier Svience Inc-
dc.source.urihttp://dx.doi.org/10.1007/s11605-008-0486-y-
dc.subjectLaparoscopic fundoplication-
dc.subjectGastro-esophageal reflux-
dc.subjectEsophageal pH monitoring-
dc.subjectRandomized controlled trial-
dc.titleEsophageal pH profile following laparoscopic total fundoplication compared to anterior fundoplication-
dc.typeJournal article-
dc.identifier.doi10.1007/s11605-008-0486-y-
pubs.publication-statusPublished-
dc.identifier.orcidMyers, J. [0000-0003-2157-7098]-
Appears in Collections:Aurora harvest 5
Surgery publications

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