Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/52567
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Type: Journal article
Title: Issues faced by unaffected men with a family history of prostate cancer: A multidisciplinary overview
Author: Wakefield, C.
Meiser, B.
Gaff, C.
Barratt, A.
Patel, M.
Suthers, G.
Lobb, E.
Ramsay, J.
Mann, G.
Citation: Journal of Urology, 2008; 180(1):38-46
Publisher: Lippincott Williams & Wilkins
Issue Date: 2008
ISSN: 0022-5347
1527-3792
Statement of
Responsibility: 
C.E. Wakefield, B. Meiser, C.L. Gaff, A. Barratt, M.I. Patel, G. Suthers, E.A. Lobb, J. Ramsay and G.J. Mann
Abstract: PURPOSE: Despite the established importance of the role of family history in prostate cancer, relatively little research encompasses the psychosocial issues relevant to unaffected men with a family history of prostate cancer. To determine the completeness and quality of available literature on the issues faced by men with a high risk of prostate cancer, we conducted a multidisciplinary review of the literature to provide some guidance on the information that clinicians might provide to men who are concerned about family history. MATERIALS AND METHODS: A structured literature search was conducted by a multidisciplinary team of clinicians and researchers who reviewed the medical and psychosocial literature, and identified 21 relevant studies. RESULTS: Research suggests that many high risk patients are concerned about the risk of prostate cancer, and some may significantly overestimate that risk. Several studies have shown high screening rates among high risk patients and high levels of interest in genetic testing for prostate cancer risk should it become available, yet many men also report a desire for more information about their personal risk and risk management options. CONCLUSIONS: Given the lack of clear data on the efficacy of prostate cancer screening among high risk patients, clinicians could consider providing men who are concerned about family history with information on their personal risk, help them to clarify the potential benefits, limitations and harms of prostate cancer screening in their situation, and then support their choice regarding the management of prostate cancer risk.
Keywords: prostatic neoplasms; risk factors; psychology
RMID: 0020080870
DOI: 10.1016/j.juro.2008.03.020
Appears in Collections:Paediatrics publications

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