Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/54810
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Power consumption and mixing in a miniaturised bioreactor |
Author: | Zhang, H. Wang, W. Fan, S. |
Citation: | Progress in Natural Science: communication of state key laboratories of China, 2005; 15(13):117-123 |
Publisher: | Taylor & Francis Ltd |
Issue Date: | 2005 |
ISSN: | 1002-0071 1745-5391 |
Statement of Responsibility: | Zhang, Hu; Wang, Weixiang and Fan, Shengdi |
Abstract: | Microbial fermentation plays an important role in digesting renewable biomass, in particular lignocellulose to generate new sources of chemical raw material and energy. The increasing number of genetic and process permutations during screening for process optimizations drives a strong demand for obtaining accurate biological and process data in short time frames and at low cost. A novel miniaturised bioreactor with a working volume of 7mL was fabricated to meet the requirements of fermentation process development. The engineering parameters including power consumption and mixing time were characterised and compared with those in a 7 L bioreactor with two standard Rushton impellers. Computational results in the 7L bioreactor were in good agreement with the literature and his approach was applied to this miniaturised bioreactor. Power number for the impellers used in the miniaturised reactor was found to vary with the detailed impeller geometrical characteristics, including the blade width, length and thickness. Mixing time in this miniaturised bioreactor was calculated to be around 0.2 s, shorter than the time required for metabolic regulations for some cells. This miniaturised bioreactor could dramatically change the fermentation process development. |
Keywords: | fermentation process miniaturised bioreactor computational fluid dynamics power number mixing time |
DOI: | 10.1080/10020070512330017 |
Published version: | http://dx.doi.org/10.1080/10020070512330017 |
Appears in Collections: | Aurora harvest 5 Chemical Engineering publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.