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dc.contributor.authorKhoo, J.en
dc.contributor.authorRayner, C.en
dc.contributor.authorJones, K.en
dc.contributor.authorHorowitz, M.en
dc.identifier.citationExpert Review of Gastroenterology and Hepatology, 2009; 3(2):167-181en
dc.description.abstractGastroparesis is characterized by upper gastrointestinal symptoms associated with delayed gastric emptying, without mechanical obstruction. However, symptoms do not correlate well with the magnitude of delay in gastric emptying. Diabetes mellitus and surgery are the most common causes, although more than 30% of cases are idiopathic. Coordination of insulin action with nutrient delivery is important in diabetics, as postprandial blood glucose levels and gastric emptying are interdependent, and gastroparesis probably represents a major cause of poor glycemic control. Scintigraphy is the gold standard for measuring gastric emptying. Current treatment mainly involves the use of prokinetic drugs. Pyloric botulinum toxin injection and gastric electrical stimulation require more evidence from controlled studies before their use can be recommended. Surgical options remain inadequately studied.en
dc.description.statementofresponsibilityJoan Khoo, Christopher K. Rayner, Karen L. Jones and Michael Horowitzen
dc.publisherExpert Reviews Ltd.en
dc.subjectHumans; Gastroparesis; Diabetes Complications; Gastrointestinal Agents; Electric Stimulation Therapy; Feeding Behavior; Gastric Emptyingen
dc.titlePathophysiology and management of gastroparesisen
dc.typeJournal articleen
pubs.library.collectionMedicine publicationsen
dc.identifier.orcidRayner, C. [0000-0002-5527-256X]en
dc.identifier.orcidJones, K. [0000-0002-1155-5816]en
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]en
Appears in Collections:Medicine publications

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