Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Type: Journal article
Title: Combination pharmacotherapy in unipolar depression
Author: Ng, F.
Dodd, S.
Berk, M.
Citation: Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders, 2006; 6(7):1049-1060
Publisher: Expert Reviews Ltd.
Issue Date: 2006
ISSN: 1473-7175
Statement of
Ng, F; Dodd, S and Berk M.
Abstract: It is estimated that between 60 and 80% of those with major depressive disorder do not achieve full symptomatic remission from first-line antidepressant monotherapy. Residual depressive symptoms substantially impair quality of life and add to the risk of recurrence. It is now clear that depression would benefit from more vigorous treatment, in order to ameliorate its disease burden. While there are established algorithms in situations of treatment resistance, the use of combination pharmacotherapy in unipolar depression is a relatively under-investigated area of treatment and may be an effective and tolerable strategy that maximizes the available resources. This paper reviews the current evidence for combination pharmacotherapy in unipolar depression and discusses its clinical applications.
Keywords: Humans
Antipsychotic Agents
Antidepressive Agents
Drug Combinations
Treatment Outcome
Drug Therapy
Drug Administration Schedule
Depressive Disorder
Dose-Response Relationship, Drug
Drug Synergism
Clinical Trials as Topic
Practice Guidelines as Topic
Practice Patterns, Physicians'
DOI: 10.1586/14737175.6.7.1049
Description (link):
Published version:
Appears in Collections:Aurora harvest 5
Psychiatry publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.