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Type: Journal article
Title: Consistent and reproducible slice selection in rodent brain using a novel stereotaxic device for MRI
Author: Fricke, S.
Vink, R.
Chiodo, C.
Cernak, I.
Ileva, L.
Faden, A.
Citation: Journal of Neuroscience Methods, 2004; 136(1):99-102
Publisher: Elsevier Science BV
Issue Date: 2004
ISSN: 0165-0270
Statement of
S. T. Fricke, R. Vink, C. Chiodo, I. Cernak, L. Ileva and A. I. Faden
Abstract: Typically small animal radiological images are obtained after placing the animal in the center of the imaging device using beds or platforms, and then adjusting the position after obtaining a scout image. Such a process does not permit the reproducible visualization of the same anatomical plane with repeated examinations. We have developed a device that allows stereotaxic placement of an animal in precisely the same position for repeated examinations. The instrument incorporates a full range of physiological monitoring and life support systems including temperature control, anesthesia delivery and respiratory monitoring. Using magnetic resonance imaging (MRI), the accuracy and reliability of this device is demonstrated in a rat traumatic brain injury (TBI) model.
Keywords: stereotaxic; rat; mouse; magnetic resonance spectroscopy; CT; neurotrauma; stroke; PET
Description: Available online 18 March 2004.
Rights: Copyright © 2004 Elsevier B.V. All rights reserved.
RMID: 0020040464
DOI: 10.1016/j.jneumeth.2004.01.003
Appears in Collections:Pathology publications

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