Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/57485
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dc.contributor.authorFraser, C.en
dc.contributor.authorDiener, K.en
dc.contributor.authorBrown, M.en
dc.contributor.authorHayball, J.en
dc.date.issued2007en
dc.identifier.citationExpert Review of Vaccines, 2007; 6(4):559-578en
dc.identifier.issn1476-0584en
dc.identifier.issn1744-8395en
dc.identifier.urihttp://hdl.handle.net/2440/57485-
dc.description.abstractWhile vaccination continues to be the most successful interventionist health policy to date, infectious disease remains a significant cause of death worldwide. A primary reason that vaccination is not able to generate effective immunity is a lack of appropriate adjuvants capable of initiating the desired immune response. Adjuvant combinations can potentially overcome this problem; however, the possible permutations to consider, which include the route and kinetics of vaccination, as well as combinations of adjuvants, are practically limitless. This review aims to summarize the current understanding of adjuvants and related immunological processes and how this knowledge can and has been applied to the strategic selection of adjuvant combinations as components of vaccines against human infectious disease.en
dc.description.statementofresponsibilityFraser, CK; Diener, KR; Brown, MP. and Hayball, JD.en
dc.description.urihttp://www.ncbi.nlm.nih.gov/pubmed/17669010en
dc.language.isoenen
dc.publisherFuture Drugs Ltd.en
dc.subjectDendritic Cells; Immune System; Animals; Humans; Virion; Alum Compounds; Saponins; Vaccines, DNA; Vaccines; Adjuvants, Immunologic; Emulsions; Drug Delivery Systems; Immunity, Mucosal; Immunologic Memory; Genetic Vectors; Immunity, Innateen
dc.titleImproving vaccines by incorporating immunological coadjuvantsen
dc.typeJournal articleen
dc.identifier.rmid0020072328en
dc.identifier.doi10.1586/14760584.6.4.559en
dc.identifier.pubid47752-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidDiener, K. [0000-0001-8417-5542]en
dc.identifier.orcidBrown, M. [0000-0002-5796-1932]en
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