Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/57672
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Type: Journal article
Title: Analysis of SINE and LINE repeat content of Y chromosomes in the platypus, Ornithorhynchus anatinus
Author: Kortschak, R.
Tsend-Ayush, E.
Grutzner, F.
Citation: Reproduction Fertility and Development, 2009; 21(8):964-975
Publisher: C S I R O Publishing
Issue Date: 2009
ISSN: 1031-3613
Statement of
Responsibility: 
Kortschak, RD; Tsend-Ayush, E. and Grutzner, F.
Abstract: Monotremes feature an extraordinary sex-chromosome system that consists of five X and five Y chromosomes in males. These sex chromosomes share homology with bird sex chromosomes but no homology with the therian X. The genome of a female platypus was recently completed, providing unique insights into sequence and gene content of autosomes and X chromosomes, but no Y-specific sequence has so far been analysed. Here we report the isolation, sequencing and analysis of approximately 700 kb of sequence of the non-recombining regions of Y2, Y3 and Y5, which revealed differences in base composition and repeat content between autosomes and sex chromosomes, and within the sex chromosomes themselves. This provides the first insights into repeat content of Y chromosomes in platypus, which overall show similar patterns of repeat composition to Y chromosomes in other species. Interestingly, we also observed differences between the various Y chromosomes, and in combination with timing and activity patterns we provide an approach that can be used to examine the evolutionary history of the platypus sex-chromosome chain.
Keywords: genome evolution; repetitive element; Y-chromosome evolution
Rights: © CSIRO 2009
RMID: 0020093147
DOI: 10.1071/RD09084
Grant ID: http://purl.org/au-research/grants/arc/DP0664267
Published version: http://www.publish.csiro.au/issue/4849.htm
Appears in Collections:Molecular and Biomedical Science publications
Environment Institute Leaders publications

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