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https://hdl.handle.net/2440/57780
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dc.contributor.author | Heath, C. | - |
dc.contributor.author | Slavin, M. | - |
dc.contributor.author | Sorrell, T. | - |
dc.contributor.author | Handke, R. | - |
dc.contributor.author | Harun, A. | - |
dc.contributor.author | Phillips, M. | - |
dc.contributor.author | Nguyen, Q. | - |
dc.contributor.author | Delhaes, L. | - |
dc.contributor.author | Ellis, D. | - |
dc.contributor.author | Meyer, W. | - |
dc.contributor.author | Chen, S. | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Clinical Microbiology and Infection, 2009; 15(7):689-693 | - |
dc.identifier.issn | 1198-743X | - |
dc.identifier.issn | 1469-0691 | - |
dc.identifier.uri | http://hdl.handle.net/2440/57780 | - |
dc.description | Article first published online: 22 JUN 2009 | - |
dc.description.abstract | Australia-wide population-based surveillance for scedosporiosis identified 180 cases, with 118 (65.6%) cases of colonization and 62 (34.4%) cases of infection. Predisposing factors for isolation of Scedosporium spp. included chronic lung disease in 37.8% and malignancy in 21.7% of cases. Predictors of invasive disease (n = 62) included haematological stem cell transplantation (n = 7), leukaemia (n = 16) and diabetes mellitus (n = 8). Of 183 phenotypically-speciated isolates, 75 (41%) were Scedosporium prolificans (risk factors: haematologic cancer (n = 17), neutropaenia (n = 14)) and 108 (59%) had Scedosporium apiospermum/Pseudallescheria boydii phenotype [risk factor: diabetes (n = 15)]. Scedosporium prolificans (p 0.01) and leukaemia (p 0.03) independently predicted death. Epidemiological and antifungal susceptibility profiles of Scedosporium aurantiacum (prevalence ≥15.8%) and S. apiospermum were similar. No patient with S. aurantiacum infection (n = 6) died. This is the first description of clinical features associated with S. aurantiacum. | - |
dc.description.statementofresponsibility | C. H. Heath, M. A. Slavin, T. C. Sorrell, R. Handke, A. Harun, M. Phillips, Q. Nguyen, L. Delhaes, D. Ellis, W. Meyer and S. C. A. Chen, on behalf of the Australian Scedosporium Study Group | - |
dc.language.iso | en | - |
dc.publisher | Blackwell Science Ltd | - |
dc.rights | Journal compilation © 2009 European Society of Clinical Microbiology and Infectious Diseases | - |
dc.source.uri | http://dx.doi.org/10.1111/j.1469-0691.2009.02802.x | - |
dc.subject | Epidemiology | - |
dc.subject | Scedosporium | - |
dc.subject | Scedosporium aurantiacum | - |
dc.title | Population-based surveillance for scedosporiosis in Australia: epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/j.1469-0691.2009.02802.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Ellis, D. [0000-0002-7283-4667] | - |
Appears in Collections: | Aurora harvest Molecular and Biomedical Science publications |
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