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|Title:||Reasons for improved survival from ovarian cancer in New South Wales, Australia, between 1980 and 2003: Implications for cancer control|
|Citation:||International Journal of Gynecological Cancer, 2009; 19(4):591-599|
|Publisher:||Blackwell Science Inc|
|Tracey, Elizabeth; Roder, David; Francis, Jane; Zorbas, Helen M; Hacker, Neville F; and Bishop, James F.|
|Abstract:||We analyzed New South Wales Central Cancer Registry data for 1980-2003, to determine time trends in case fatality from ovarian cancer, after adjusting for stage, histological, and sociodemographic factors, and to consider service-delivery and research implications. After adjusting for covariates, the relative risk (95% confidence limit) of ovarian-cancer death reduced to 0.51 (0.46, 0.57) for 1999-2003 compared with 1980-1983. Relative risks were higher for adenocarcinomas and other specified and unspecified cancers than serous carcinomas, but lower for endometrioid carcinomas, sex cord-stromal and germ cell tumors. The probability of diagnosis with localized as opposed to more advanced disease was lower in older patients, the lowest socioeconomic stratum, women born in non-English-speaking countries, and more recent diagnostic periods. Approximately 61% of ovarian cancers had distant metastases at diagnosis in 1999-2003. Poorer survivals apply to older patients. Research directed at finding an effective screening test for epithelial ovarian cancer remains a priority.|
|Keywords:||Humans; Ovarian Neoplasms; Mass Screening; Neoplasm Staging; Registries; Logistic Models; Proportional Hazards Models; Age Factors; Socioeconomic Factors; Adult; Aged; Aged, 80 and over; Middle Aged; New South Wales; Female|
|Rights:||Copyright © 2009 by IGCS and ESGO|
|Appears in Collections:||Public Health publications|
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