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Type: Journal article
Title: Effects of postoperative radiotherapy for temporomandibular joint ankylosis after gap arthroplasty: An animal study using sheep
Author: Takaishi, M.
Kurita, K.
Hatano, Y.
Matsuura, H.
Borg, M.
Goss, A.
Citation: Journal of Oral and Maxillofacial Surgery, 2010; 68(8):1763-1769
Publisher: W B Saunders Co
Issue Date: 2010
ISSN: 0278-2391
Statement of
Makoto Takaishi, Kenichi Kurita, Yuko Hatano, Hiroaki Matsuura, Martin Borg and N. Alastair Goss
Abstract: <h4>Purpose</h4>The aim of the present study was to examine the effects of postoperative irradiation on reducing heterotopic bone formation after gap arthroplasty release of temporomandibular joint ankylosis.<h4>Materials and methods</h4>Five sheep underwent induction of right temporomandibular joint ankylosis. After 3 months, the ankylosis was released by gap arthroplasty. At 24 hours after the release, they received a single radiation dose of 10 Gy. All sheep were sacrificed at 3 months after gap arthroplasty release. The body weight, jaw opening amount, and radiographs were measured at key intervals, with histologic assessment after death. The findings were compared with those in a control group treated with gap arthroplasty without irradiation.<h4>Results</h4>The clinical measurements, radiographs, and histologic findings all revealed less evidence of reankylosis in the irradiated sheep.<h4>Conclusion</h4>The results of the present study have shown that a single radiation dose at 24 hours after gap arthroplasty for temporomandibular joint ankylosis inhibits heterotopic ossification.
Keywords: Animals
Temporomandibular Joint Disorders
Ossification, Heterotopic
Radiotherapy, Adjuvant
Postoperative Care
Rights: Copyright © 2010 American Association of Oral and Maxillofacial Surgeons All rights reserved.
DOI: 10.1016/j.joms.2009.09.009
Appears in Collections:Aurora harvest
Surgery publications

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