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|Title:||Effects of postoperative radiotherapy for temporomandibular joint ankylosis after gap arthroplasty: An animal study using sheep|
|Citation:||Journal of Oral and Maxillofacial Surgery, 2010; 68(8):1763-1769|
|Publisher:||W B Saunders Co|
|Makoto Takaishi, Kenichi Kurita, Yuko Hatano, Hiroaki Matsuura, Martin Borg and N. Alastair Goss|
|Abstract:||PURPOSE: The aim of the present study was to examine the effects of postoperative irradiation on reducing heterotopic bone formation after gap arthroplasty release of temporomandibular joint ankylosis. MATERIALS AND METHODS: Five sheep underwent induction of right temporomandibular joint ankylosis. After 3 months, the ankylosis was released by gap arthroplasty. At 24 hours after the release, they received a single radiation dose of 10 Gy. All sheep were sacrificed at 3 months after gap arthroplasty release. The body weight, jaw opening amount, and radiographs were measured at key intervals, with histologic assessment after death. The findings were compared with those in a control group treated with gap arthroplasty without irradiation. RESULTS: The clinical measurements, radiographs, and histologic findings all revealed less evidence of reankylosis in the irradiated sheep. CONCLUSION: The results of the present study have shown that a single radiation dose at 24 hours after gap arthroplasty for temporomandibular joint ankylosis inhibits heterotopic ossification.|
|Keywords:||Animals; Sheep; Temporomandibular Joint Disorders; Ankylosis; Ossification, Heterotopic; Radiotherapy, Adjuvant; Postoperative Care; Arthroplasty|
|Rights:||Copyright © 2010 American Association of Oral and Maxillofacial Surgeons All rights reserved.|
|Appears in Collections:||Surgery publications|
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