Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/59825
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Type: Journal article
Title: Effects of postoperative radiotherapy for temporomandibular joint ankylosis after gap arthroplasty: An animal study using sheep
Author: Takaishi, M.
Kurita, K.
Hatano, Y.
Matsuura, H.
Borg, M.
Goss, A.
Citation: Journal of Oral and Maxillofacial Surgery, 2010; 68(8):1763-1769
Publisher: W B Saunders Co
Issue Date: 2010
ISSN: 0278-2391
1531-5053
Statement of
Responsibility: 
Makoto Takaishi, Kenichi Kurita, Yuko Hatano, Hiroaki Matsuura, Martin Borg and N. Alastair Goss
Abstract: PURPOSE: The aim of the present study was to examine the effects of postoperative irradiation on reducing heterotopic bone formation after gap arthroplasty release of temporomandibular joint ankylosis. MATERIALS AND METHODS: Five sheep underwent induction of right temporomandibular joint ankylosis. After 3 months, the ankylosis was released by gap arthroplasty. At 24 hours after the release, they received a single radiation dose of 10 Gy. All sheep were sacrificed at 3 months after gap arthroplasty release. The body weight, jaw opening amount, and radiographs were measured at key intervals, with histologic assessment after death. The findings were compared with those in a control group treated with gap arthroplasty without irradiation. RESULTS: The clinical measurements, radiographs, and histologic findings all revealed less evidence of reankylosis in the irradiated sheep. CONCLUSION: The results of the present study have shown that a single radiation dose at 24 hours after gap arthroplasty for temporomandibular joint ankylosis inhibits heterotopic ossification.
Keywords: Animals; Sheep; Temporomandibular Joint Disorders; Ankylosis; Ossification, Heterotopic; Radiotherapy, Adjuvant; Postoperative Care; Arthroplasty
Rights: Copyright © 2010 American Association of Oral and Maxillofacial Surgeons All rights reserved.
RMID: 0020100215
DOI: 10.1016/j.joms.2009.09.009
Appears in Collections:Surgery publications

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