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PreviewIssue DateTitleAuthor(s)
2022Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24Davidson, S.; Yu, C.-H.; Steiner, A.; Ebstein, F.; Baker, P.J.; Jarur-Chamy, V.; Hrovat Schaale, K.; Laohamonthonkul, P.; Kong, K.; Calleja, D.J.; Harapas, C.R.; Balka, K.R.; Mitchell, J.; Jackson, J.T.; Geoghegan, N.D.; Moghaddas, F.; Rogers, K.L.; Mayer-Barber, K.D.; De Jesus, A.A.; De Nardo, D.; et al.
2022TLR7 gain-of-function genetic variation causes human lupusBrown, G.J.; Cañete, P.F.; Wang, H.; Medhavy, A.; Bones, J.; Roco, J.A.; He, Y.; Qin, Y.; Cappello, J.; Ellyard, J.I.; Bassett, K.; Shen, Q.; Burgio, G.; Zhang, Y.; Turnbull, C.; Meng, X.; Wu, P.; Cho, E.; Miosge, L.A.; Andrews, T.D.; et al.
2019Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemiaBell, C.C.; Fennell, K.A.; Chan, Y.C.; Rambow, F.; Yeung, M.M.; Vassiliadis, D.; Lara, L.; Yeh, P.; Martelotto, L.G.; Rogiers, A.; Kremer, B.E.; Barbash, O.; Mohammad, H.P.; Johanson, T.M.; Burr, M.L.; Dhar, A.; Karpinich, N.; Tian, L.; Tyler, D.S.; MacPherson, L.; et al.
2021CDK4/6 inhibition promotes antitumor immunity through the induction of T-cell memoryLelliott, E.J.; Kong, I.Y.; Zethoven, M.; Ramsbottom, K.M.; Martelotto, L.G.; Meyran, D.; Zhu, J.J.; Costacurta, M.; Kirby, L.; Sandow, J.J.; Lim, L.; Dominguez, P.M.; Todorovski, I.; Haynes, N.M.; Beavis, P.A.; Neeson, P.J.; Hawkins, E.D.; McArthur, G.A.; Parish, I.A.; Johnstone, R.W.; et al.
2018Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapyMarini, K.D.; Croucher, D.R.; McCloy, R.A.; Vaghjiani, V.; Gonzalez-Rajal, A.; Hastings, J.F.; Chin, V.; Szczepny, A.; Kostyrko, K.; Marquez, C.; Samantha, W.; Jayasekara, N.; Alamgeer, M.; Boolell, V.; Han, J.Z.R.; Waugh, T.; Lee, H.C.; Oakes, S.R.; Kumar, B.; Harrison, C.A.; et al.
2016A syntenic cross species aneuploidy genetic screen links RCAN1 expression to β-Cell mitochondrial dysfunction in type 2 diabetesPeiris, H.; Duffield, M.D.; Fadista, J.; Jessup, C.F.; Kashmir, V.; Genders, A.J.; McGee, S.L.; Martin, A.M.; Saiedi, M.; Morton, N.; Carter, R.; Cousin, M.A.; Kokotos, A.C.; Oskolkov, N.; Volkov, P.; Hough, T.A.; Fisher, E.M.C.; Tybulewicz, V.L.J.; Busciglio, J.; Coskun, P.E.; et al.; Scott, H.S.
2015Progesterone receptor modulates ERα action in breast cancerMohammed, H.; Russell, I.; Stark, R.; Rueda, O.; Hickey, T.; Tarulli, G.; Serandour, A.; Birrell, S.; Bruna, A.; Saadi, A.; Menon, S.; Hadfield, J.; Pugh, M.; Raj, G.; Brown, G.; D'Santos, C.; Robinson, J.; Silva, G.; Launchbury, R.; Perou, C.; et al.
2012PRRT2 mutations cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndromeHeron, S.; Grinton, B.; Kivity, S.; Afawi, Z.; Zuberi, S.; Hughes, J.; Pridmore, C.; Hodgson, B.; Iona, X.; Sadleir, L.; Pelekanos, J.; Herlenius, E.; Goldberg-Stern, H.; Bassan, H.; Haan, E.; Korczyn, A.; Gardner, A.; Corbett, M.; Gecz, J.; Thomas, P.; et al.
2011Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucomaKhan, K.; Rudkin, A.; Parry, D.; Burdon, K.; McKibbin, M.; Logan, C.; Abdelhamed, Z.; Muecke, J.; Fernandez-Fuentes, N.; Laurie, K.; Shires, M.; Fogarty, R.; Carr, I.; Poulter, J.; Morgan, J.; Mohamed, M.; Jafri, H.; Raashid, Y.; Meng, N.; Piseth, H.; et al.
2010Mutations in the small GTPase gene RAB39B are responsible for X-linked mental retardation associated with autism, epilepsy, and macrocephalyGiannandrea, M.; Bianchi, V.; Mignogna, M.; Sirri, A.; Carrabino, S.; D'Elia, E.; Vecellio, M.; Russo, S.; Cogliati, F.; Larizza, L.; Ropers, H.; Tzschach, A.; Kalscheuer, V.; Oehl-Jaschkowitz, B.; Skinner, C.; Schwartz, C.; Gecz, J.; Van Esch, H.; Raynaud, M.; Chelly, J.; et al.