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PreviewIssue DateTitleAuthor(s)
2007Pathologic changes in mice induced by subtilase cytotoxin, a potent new Escherichia coli ABâ‚… toxin that targets the endoplasmic reticulumWang, H.; Paton, J.; Paton, A.
2009Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cellsBacker, J.; Krivoshein, A.; Hamby, C.; Pizzonia, J.; Gilbert, K.; Ray, Y.; Brand, H.; Paton, A.; Paton, J.; Backer, M.
2009Acquisition of Anergy to Proinflammatory Cytokines in Nonimmune Cells through Endoplasmic Reticulum Stress Response: A Mechanism for Subsidence of InflammationHayakawa, K.; Hiramatsu, N.; Okamura, M.; Yamazaki, H.; Nakajima, S.; Yao, J.; Paton, A.; Paton, J.; Kitamura, M.
2009A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide-induced inflammatory responses, depending on its capacity to induce the unfolded protein responseHarama, D.; Koyama, K.; Mukai, M.; Shimokawa, N.; Miyata, M.; Nakamura, Y.; Ohnuma, Y.; Ogawa, H.; Matsuoka, S.; Paton, A.; Paton, J.; Kitamura, M.; Nakao, A.
2007Suppression of cytokine response by GATA inhibitor K-7174 via unfolded protein responseTakano, Y.; Hiramatsu, N.; Okamura, M.; Hayakawa, K.; Shimada, T.; Kasai, A.; Yokouchi, M.; Shitamura, A.; Yao, J.; Paton, A.; Paton, J.; Kitamura, M.
2006AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiPPaton, A.; Beddoe, T.; Thorpe, C.; Whisstock, J.; Wilce, M.; Rossjohn, J.; Talbot, U.; Paton, J.
2010Escherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/BakMay, K.; Paton, J.; Paton, A.
2009Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytesHu, C.; Dougan, S.; Winter, S.; Paton, A.; Paton, J.; Ploegh, H.