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|Title:||A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies|
|Citation:||Australasian Journal of Dermatology, 2007; 48(1):46-49|
|Publisher:||Blackwell Publishing Asia|
|Annette Pearce, Catherine Reid, Amanda Gramp and Shireen Sidhu|
|Abstract:||An 83-year-old Caucasian woman presented with a 25-year history of an itchy, eczematous blistering eruption affecting her trunk and acral sites. She had a past history of adenocarcinoma of the lung, colorectal carcinoma and bladder carcinoma. Several skin biopsies consistently showed features of a spongiotic process. Direct and indirect immunofluorescence studies were repeatedly negative, excluding the possibility of an autoimmune blistering disorder. A skin biopsy several years later, however, showed histological and immunophenotypic features of mycosis fungoides. The literature on this rare phenotype of cutaneous T-cell lymphoma generally portrays a negative prognosis. Our case illustrates an excellent prognosis with stable disease 30 years after onset.|
|Keywords:||atypical lymphocyte; cutaneous T-cell lymphoma; eczematous histology; immunophenotype|
|Rights:||© 2007 The Authors|
|Appears in Collections:||Medicine publications|
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