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Type: Journal article
Title: A 30-year history of CD4+ vesiculo-bullous mycosis fungoides and multiple visceral malignancies
Author: Pearce, A.
Reid, C.
Gramp, A.
Sidhu, S.
Citation: Australasian Journal of Dermatology, 2007; 48(1):46-49
Publisher: Blackwell Publishing Asia
Issue Date: 2007
ISSN: 0004-8380
Statement of
Annette Pearce, Catherine Reid, Amanda Gramp and Shireen Sidhu
Abstract: An 83-year-old Caucasian woman presented with a 25-year history of an itchy, eczematous blistering eruption affecting her trunk and acral sites. She had a past history of adenocarcinoma of the lung, colorectal carcinoma and bladder carcinoma. Several skin biopsies consistently showed features of a spongiotic process. Direct and indirect immunofluorescence studies were repeatedly negative, excluding the possibility of an autoimmune blistering disorder. A skin biopsy several years later, however, showed histological and immunophenotypic features of mycosis fungoides. The literature on this rare phenotype of cutaneous T-cell lymphoma generally portrays a negative prognosis. Our case illustrates an excellent prognosis with stable disease 30 years after onset.
Keywords: atypical lymphocyte
cutaneous T-cell lymphoma
eczematous histology
Rights: © 2007 The Authors
DOI: 10.1111/j.1440-0960.2007.00333.x
Appears in Collections:Aurora harvest
Medicine publications

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