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https://hdl.handle.net/2440/60706
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dc.contributor.author | Gillman, M. | - |
dc.contributor.author | Oakey, H. | - |
dc.contributor.author | Baghurst, P. | - |
dc.contributor.author | Volkmer, R. | - |
dc.contributor.author | Robinson, J. | - |
dc.contributor.author | Crowther, C. | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Diabetes Care, 2010; 33(5):964-968 | - |
dc.identifier.issn | 0149-5992 | - |
dc.identifier.issn | 1935-5548 | - |
dc.identifier.uri | http://hdl.handle.net/2440/60706 | - |
dc.description.abstract | OBJECTIVE--Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess the effect of treatment for mild GDM on the BMI of 4- to 5-year-old children. RESEARCH DESIGN AND METHODS--Participants were 199 mothers who participated in a randomized controlled trial of the treatment of mild GDM during pregnancy and their children. Trained nurses measured the height and weight of the children at preschool visits in a state-wide surveillance program in the state of South Australia. The main outcome measure was age- and sex-specific BMI Z score based on standards of the International Obesity Task Force. RESULTS--At birth, prevalence of macrosomia (birth weight [greater than or equal to] 4,000 g) was 5.3% among the 94 children whose mothers were in the intervention group, and 21.9% among the 105 children in the routine care control group. At 4- to 5-years-old, mean (SD) BMI Z score was 0.49 (1.20) in intervention children and 0.41 (1.40) among controls. The difference between treatment groups was 0.08 (95% CI -0.29 to 0.44), an estimate minimally changed by adjustment for maternal race, parity, age, and socio-economic index (0.08 [-0.29 to 0.45]). Evaluating BMI [greater than or equal to] 85th percentile rather than continuous BMI Z score gave similarly null results. CONCLUSIONS--Although treatment of GDM substantially reduced macrosomia at birth, it did not result in a change in BMI at age 4- to 5-years-old. | - |
dc.description.statementofresponsibility | Matthew W. Gillman, Helena Oakey, Peter A. Baghurst, Robert E. Volkmer, Jeffrey S. Robinson and Caroline A. Crowther | - |
dc.language.iso | en | - |
dc.publisher | Amer Diabetes Assoc | - |
dc.rights | COPYRIGHT 2010 American Diabetes Association | - |
dc.source.uri | http://dx.doi.org/10.2337/dc09-1810 | - |
dc.subject | Humans | - |
dc.subject | Diabetes, Gestational | - |
dc.subject | Fetal Macrosomia | - |
dc.subject | Prenatal Exposure Delayed Effects | - |
dc.subject | Obesity | - |
dc.subject | Insulin | - |
dc.subject | Hypoglycemic Agents | - |
dc.subject | Body Mass Index | - |
dc.subject | Prevalence | - |
dc.subject | Follow-Up Studies | - |
dc.subject | Pregnancy | - |
dc.subject | Child, Preschool | - |
dc.subject | South Australia | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | Effect of treatment of gestational diabetes mellitus on obesity in the next generation | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.2337/dc09-1810 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Oakey, H. [0000-0003-1057-7615] | - |
dc.identifier.orcid | Robinson, J. [0000-0002-4515-6039] | - |
dc.identifier.orcid | Crowther, C. [0000-0002-9079-4451] | - |
Appears in Collections: | Aurora harvest 5 Obstetrics and Gynaecology publications |
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