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Type: Journal article
Title: Murine nematode immunology in Australasia
Author: Dent, L.
Citation: Parasite Immunology, 2010; 32(8):560-571
Publisher: Blackwell Science Ltd
Issue Date: 2010
ISSN: 0141-9838
Statement of
L. A. Dent
Abstract: A relatively small number of laboratories in Australia and New Zealand have consistently published on murine models of nematode immunology, and the parasite species principally used are Heligmosomoides bakeri (previously Heligmosomoides polygyrus), Strongyloides ratti, Nippostrongylus brasiliensis and Toxocara canis. These research groups have made significant contributions to both fundamental immunology and more specialized issues in host–parasite relationships. Topics addressed include immune regulation, including the expression and control of Type 2 cytokines and the responses induced, innate and adaptive host-protective mechanisms, antigen expression and immune evasion strategies utilized by parasitic helminths. This review addresses the last 30 years of research and identifies areas in which major progress can be made, given appropriate resources.
Keywords: Asthma
Rights: © 2010 Blackwell Publishing
DOI: 10.1111/j.1365-3024.2010.01233.x
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Appears in Collections:Aurora harvest
Molecular and Biomedical Science publications

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