Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/6157
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Type: Journal article
Title: Feasibility of conducting cardiovascular outcome research in Australian General Practice - results from the ANBP2 Pilot Study
Author: Reid, C.
Nelson, M.
Beckinsale, P.
Ryan, P.
Marley, J.
Wing, L.
Beilin, L.
Brown, M.
Jennings, G.
Johnston, C.
McNeil, J.
Morgan, T.
Shaw, J.
Steven, I.
West, M.
Citation: Clinical and Experimental Pharmacology and Physiology, 1997; 24(5):370-373
Publisher: Blackwell Science
Issue Date: 1997
ISSN: 0305-1870
1440-1681
Abstract: 1. The present study aimed to determine the feasibility of conducting a 5 year cardiovascular outcome trial of the treatment of 6000 elderly hypertensive patients in Australian general practices. 2. General practitioners (GPs) were invited to participate by mail and personal follow-up. Patient records were reviewed to identify subjects for a blood pressure (BP) screening programme. Blood pressure was measured on three occasions and eligible subjects were included if the average BP was geqslant R: gt-or-equal, slanted 160 mmHg systolic or geqslant R: gt-or-equal, slanted 90 mmHg diastolic if systolic BP was geqslant R: gt-or-equal, slanted 140 mmHg. 3. Seven hundred and forty-one GPs were approached and 89 were enrolled in the study (12% of mail invites and 75% of those receiving a personal contact). In 16 practices where screening was completed, 82 000 records were reviewed to identify 4% patients eligible for screening. Twenty-two per cent of eligible subjects attended screening. Of 1938 subjects screened, 180 (9%) had BP 5=160/90 mmHg. Forty-seven percent of subjects (n = 916) were receiving antihypertensive therapy and 184 (20%) were withdrawn from therapy. One hundred and sixteen (63%) of these subjects had BP return to study entry levels within 6 weeks. Fifty-seven newly diagnosed and 81 previously treated subjects were randomized (7% of the screened population). 4. Based on the high participation rate of GPs, the response rate of patients to attend a BP screening programme and the 7% randomization to screening ratio for entry into the study, the ANBP2 pilot study has demonstrated that it is feasible to recruit subjects from Australian general practices to a cardiovascular outcome trial.
Keywords: cardiovascular outcome; elderly; general practice; hypertension; pilot study
Description: Article first published online: 28 JUN 2007
RMID: 0030006036
DOI: 10.1111/j.1440-1681.1997.tb01204.x
Appears in Collections:General Practice publications

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