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Type: Journal article
Title: Deep brain stimulation for essential tremor: A systematic review
Author: Della Flora, E.
Perera, C.
Cameron, A.
Maddern, G.
Citation: Movement Disorders, 2010; 25(11):1550-1559
Publisher: Wiley-Liss
Issue Date: 2010
ISSN: 0885-3185
Statement of
Eliana Della Flora, Caryn L. Perera, Alun L. Cameron, and Guy J. Maddern
Abstract: Deep brain stimulation (DBS) is a neurosurgical treatment, which has proven useful in treating Parkinson's disease. This systematic review assessed the safety and effectiveness of DBS for another movement disorder, essential tremor. All studies concerning the use of DBS in patients with essential tremor were identified through searching of electronic databases and hand searching of reference lists. Studies were categorized as before/after DBS or DBS stimulation on/off to allow the effect of the stimulation to be analyzed separately to that of the surgery itself. A total of 430 patients who had received DBS for essential tremor were identified. Most of the reported adverse events were mild and could be treated through changing the stimulation settings. Generally, in all studies, there was a significant improvement in outcomes after DBS compared with baseline scores. In addition, DBS was significantly better in testing when the stimulation was turned on, compared with stimulation turned off or baseline. Based on Level IV evidence, DBS is possibly a safe and effective therapy for essential tremor.
Keywords: deep brain stimulation
essential tremor
systematic review
Rights: Copyright © 2010 Movement Disorder Society
DOI: 10.1002/mds.23195
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Appears in Collections:Aurora harvest 5
Surgery publications

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