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Type: Journal article
Title: Mild ovarian stimulation for IVF: 10 years later
Author: Fauser, B.
Nargund, G.
Andersen, A.
Norman, R.
Tarlatzis, B.
Boivin, J.
Ledger, W.
Citation: Human Reproduction, 2010; 25(11):2678-2684
Publisher: Oxford Univ Press
Issue Date: 2010
ISSN: 0268-1161
Statement of
Bart C. J. M. Fauser, Geeta Nargund, Anders Nyboe Andersen, Robert Norman, Basil Tarlatzis, Jacky Boivin and William Ledger
Abstract: Ovarian stimulation to achieve multiple follicle development has been an integral part of IVF treatment. In the context of improved laboratory performance, the need for a large number of oocytes as an integral part of a successful IVF programme may be questioned. The aim of the current debate is to summarize the studies performed during the last decade to develop the concept of mild stimulation aiming to obtain fewer than eight oocytes. Here we examine the balance between IVF success and patient discomfort, and complications and cost, and how these might improve by simpler ovarian stimulation protocols aimed at retrieving fewer oocytes. We intend to analyse why progress has been rather slow and why there is much resistance to mild stimulation. Finally, presumed useful directions for future research will be discussed.
Keywords: Mild ovarian stimulation
GnRH antagonist
Rights: © The Author 2010. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.
DOI: 10.1093/humrep/deq247
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Appears in Collections:Aurora harvest 5
Obstetrics and Gynaecology publications

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