Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/62305
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Type: Journal article
Title: Altered fractionation in radiotherapy: From radiobiological rationale to therapeutic gain
Author: Marcu, L.
Citation: Cancer Treatment Reviews, 2010; 36(8):606-614
Publisher: W B Saunders Co Ltd
Issue Date: 2010
ISSN: 0305-7372
1532-1967
Statement of
Responsibility: 
Loredana G. Marcu
Abstract: The implementation of altered fractionation schedules in clinical practice came as a need to improve loco-regional control and survival in those cancer patient groups which did not respond satisfactorily to conventionally fractionated radiotherapy. The current review aims to present the radiobiological rationale behind various non-conventional treatment schedules including the encountered challenges, through a compilation of clinical studies/trials and their contribution towards therapeutic gain.
Keywords: Altered fractionation
Radiotherapy
Therapeutic gain
Trial
Rights: © 2010 Elsevier Ltd. All rights reserved.
DOI: 10.1016/j.ctrv.2010.04.004
Published version: http://dx.doi.org/10.1016/j.ctrv.2010.04.004
Appears in Collections:Aurora harvest 5
Chemistry and Physics publications

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