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Type: Journal article
Title: Consistent chemical form of Cd in liver and kidney tissues in rats dosed with a range of Cd treatments: XAS of intact tissues
Author: Diacomanolis, V.
Ng, J.
Sadler, R.
Nomura, M.
Noller, B.
Harris, H.
Citation: Chemical Research in Toxicology, 2010; 23(11):1647-1649
Publisher: Amer Chemical Soc
Issue Date: 2010
ISSN: 0893-228X
Statement of
Violet Diacomanolis, Jack C. Ng, Ross Sadler, Masaharu Nomura, Barry N. Noller and Hugh H. Harris
Abstract: X-ray absorption spectroscopy of frozen intact tissues shows that in rats exposed to a range of treatments involving cadmium, alone or in combination with other metal ions, the coordination environment of cadmium is consistent in both the liver and kidney. Comparison of the spectra from the rat tissues to biologically relevant model compounds indicates that the vast majority of the cadmium is bound to metallothionein in these tissues.
Keywords: Liver
Environmental Pollutants
Models, Chemical
X-Ray Absorption Spectroscopy
Rights: © 2010 American Chemical Society
DOI: 10.1021/tx100333r
Grant ID:
Appears in Collections:Aurora harvest 5
Chemistry and Physics publications
Environment Institute publications

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