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Type: Journal article
Title: Working memory in posttraumatic stress disorder - An event-related potential study
Author: Galletly, C.
Clark, C.
McFarlane, A.
Weber, D.
Citation: Journal of Traumatic Stress, 2001; 14(2):295-309
Publisher: Kluwer Academic/Plenum Publ
Issue Date: 2001
ISSN: 0894-9867
Statement of
Cherrie Galletly, C. Richard Clark, Alexander C. McFarlane and Darren L. Weber
Abstract: This study examined ERP topography during the updating and the utilization of working memory in subjects with PTSD. Event-related potentials of 18 participants with PTSD and 18 controls were recorded from 32 scalp electrodes during an auditory target detection task requiring the constant updating of target identity. Midline N2 and P3 abnormalities previously noted in PTSD during target detection were replicated. Scalp topographic data revealed sustained reduction in activity over the right hemisphere during working memory updating. Executive processes were associated with brief but widespread right hemisphere reductions during the P3, followed by sustained, bilateral reduction frontally. This study identifies an abnormal pattern of cortical network function during both the updating and use of working memory in PTSD.
Keywords: posttraumatic stress disorder
working memory
event-related potentials
Description: The original publication can be found at
DOI: 10.1023/A:1011112917797
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