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Type: Journal article
Title: Generalized alopecic and cystic dermatosis in a cat: a counterpart to the hairless mouse phenotype or a unique congenital dermatosis?
Author: Neuber, A.
Van Den Broek, A.
Rhind, S.
Hill, P.
Thoday, K.
Citation: Veterinary Dermatology, 2006; 17(17):63-69
Publisher: Blackwell Science Ltd
Issue Date: 2006
ISSN: 0959-4493
Statement of
Ariane E. Neuber, Adri H. M. Van Den Broek, Susan M. Rhind, Peter B. Hill and Keith L. Thoday
Abstract: A 2-year-old, male neutered, domestic semi-long-haired cat was presented with a 1.5-year history of progressive, initially nonpruritic alopecia and malodorous greasy exudate affecting the distal extremities, trunk and neck but sparing the head and tail. The extensive alopecia and ‘seborrhoea’ were associated with severe thickening of the skin and fold formation on the dorsal head and distal extremities as well as the lateral thorax and abdomen. The hair was easily epilated, numerous milia were seen on the ventral abdomen and the caudal and lateral thighs, and mild paronychia was present. Histopathological examination of skin biopsies revealed marked cystic dilation of hair follicles and sebaceous glands with follicular hypoplasia, infundibular hyperkeratosis and variable associated inflammation. Systemic glucocorticoid therapy in combination with topical washes with chlorhexidine and miconazole resulted in a marked improvement and some hair regrowth, but the cat was subsequently lost to follow-up. The dermatosis resembles a number of conditions in other species, but it is not clear whether it is a counterpart to the hairless mutant mouse or is a unique dermatosis.
Keywords: Animals; Cats; Mice; Skin Diseases; Alopecia; Cat Diseases; Chlorhexidine; Glucocorticoids; Diagnosis, Differential; Male; Mice, Hairless
Rights: © 2006 The Authors.
RMID: 0020103513
DOI: 10.1111/j.1365-3164.2005.00492.x
Appears in Collections:Animal and Veterinary Sciences publications

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