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Type: Journal article
Title: Total Synthesis of (+)-Azinothricin and (+)-Kettapeptin
Author: Hale, K.
Manaviazar, S.
George, J.
Walters, M.
Dalby, S.
Citation: Organic Letters, 2009; 11(3):733-736
Publisher: Amer Chemical Soc
Issue Date: 2009
ISSN: 1523-7060
Statement of
Karl J. Hale, Soraya Manaviazar, Jonathan H. George, Marcus A. Walters, and Stephen M. Dalby
Abstract: Asymmetric total syntheses of (+)-azinothricin and (+)-kettapeptin have been completed through a common new pathway that exploits a highly chemoselective coupling reaction between the fully elaborated cyclodepsipeptide 5 and the glycal activated esters 3 and 4 at the final stages of both respective syntheses.
Keywords: Esters; Depsipeptides; Peptides; Molecular Structure; Stereoisomerism
Rights: Copyright © 2009 American Chemical Society
RMID: 0020105895
DOI: 10.1021/ol802817t
Appears in Collections:Chemistry publications

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