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Type: Journal article
Title: Ischaemic stroke among young people aged 15 to 50 years in Adelaide, South Australia
Author: Phillips, M.
Leyden, J.
Chong, W.
Kleinig, T.
Czapran, P.
Lee, A.
Koblar, S.
Jannes, J.
Citation: Medical Journal of Australia, 2011; 195(10):610-614
Publisher: Australasian Med Publ Co Ltd
Issue Date: 2011
ISSN: 0025-729X
Statement of
Matthew C L Phillips, James M Leyden, Woon K Chong, Tim Kleinig, Philippa Czapran, Andrew Lee, Simon A Koblar and Jim Jannes
Abstract: Objectives: To report risk factors, aetiology and neuroimaging features among a large series of young Australian patients who were admitted to hospital for a first-ever occurrence of ischaemic stroke; to analyse the effect of age, sex and ethnicity on the presence of risk factors; and to compare Australian and overseas data. Design, setting and patients: Retrospective evaluation of data for all patients aged from 15 to 50 years who were admitted to a public hospital in Adelaide, South Australia, from January 2006 to June 2010 with a primary diagnosis of ischaemic stroke. Results: Among 326 patients (184 males), the most frequent stroke risk factors overall were dyslipidaemia (187), smoking (161), hypertension (105) and obesity (92). Fifty-one patients used illicit drugs, mostly comprising marijuana and amphetamines. The most frequent stroke aetiologies overall were cardioembolism (85), arterial dissection (49), and small-vessel occlusion (31). Cardioembolism was highly prevalent among our study population compared with patients in other countries. Neuroimaging showed that more patients in our study had strokes that involved both vascular territories concurrently (9%) compared with patients in other countries. Conclusions: Risk factors, aetiology and features of ischaemic stroke among young people in Adelaide differ significantly from published data for young patients around the world. Patients in Adelaide are more likely to be obese, to be misusing marijuana and amphetamines, to suffer a cardioembolic event and to have a stroke that concurrently affects both the anterior and posterior cerebral circulation.
Keywords: Humans
Brain Ischemia
Cardiovascular Diseases
Severity of Illness Index
Risk Assessment
Survival Analysis
Retrospective Studies
Cohort Studies
Age Distribution
Sex Distribution
Middle Aged
Urban Population
South Australia
Young Adult
Rights: Copyright Australasian Medical Publishing Company
DOI: 10.5694/mja11.10558
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