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Type: Journal article
Title: Burn healing is dependent on burn site: a quantitative analysis from a porcine burn model
Author: Wang, X.
Liu, P.
Kempf, M.
Cuttle, L.
Chang, H.
Wong, M.
Kravchuk, O.
Mill, J.
Kimble, R.
Citation: Burns, 2009; 35(2):264-269
Publisher: Elsevier Sci Ltd
Issue Date: 2009
ISSN: 0305-4179
Statement of
Xue-Qing Wang, Pei-Yun Liu, Margit Kempf, Leila Cuttle, Allen Hong-En Chang, Michael Wong, Olena Kravchuk, Julie Mill, Roy M. Kimble
Abstract: This retrospective review examines healing in different sites on a porcine burn model; 24 pairs of burns on 18 pigs from other animal trials were selected for analysis. Each pair of burns was located on the either the cranial or the caudal part of the thoracic ribs region, on the same side of the animal. The burns were 40–50 cm2 in size and of uniform deep-dermal partial thickness. Caudal burns healed significantly better than cranial burns, demonstrated by earlier closure of wounds, less scar formation and better cosmesis. To our knowledge, this is the first detailed study reporting that burn healing is affected by location on a porcine burn model. We recommend that similar symmetrical burns should be used for future comparative assessments of burn healing.
Keywords: Burn; Wound healing; Porcine burn model; Site-dependent healing
Rights: Copyright © 2008 Elsevier Ltd and ISBI. All rights reserved.
RMID: 0020114337
DOI: 10.1016/j.burns.2008.05.030
Appears in Collections:Agriculture, Food and Wine publications

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