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Type: Book chapter
Title: Discussant chapter: using family-based designs in life course epidemiology
Author: Lynch, J.
Yang, S.
Citation: Family Matters: designing, analysing and understanding family-based studies in life course epidemiology, 2009 / Lawlor, D., Mishra, G. (ed./s), vol.9780199231034, pp.317-324
Publisher: Oxford University Press
Publisher Place: Oxford
Issue Date: 2009
ISBN: 0199231036
Editor: Lawlor, D.
Mishra, G.
Statement of
John Lynch and Seungmi Yang
Abstract: The three chapters in this section offer different but complementary conceptualizations of ‘family’. Morton and Rich Edwards used ‘family’ to document intergenerational concordance of reproductive outcomes, Hatch and Mishra documented how ‘family’ could be characterized as a risk exposure for later poor mental health, and Lawlor and Leon used ‘family’ as a means to control for unmeasured confounding by family characteristics to better understand causal mechanisms relating fetal growth to later disease. Lawlor and Leon’s approach is similar to that used in studies examining the possible intrauterine origins of birth weight and cognitive ability and we briefly explore that literature. Families surely matter for better understanding individual and population patterns of ill-health. If we know how families transmit different diseases across generations then it may elucidate novel or under-exploited avenues for prevention.
Keywords: life course epidemiology; family studies; twin studies; sibling studies; intergenerational studies; cognitive function; birth weight; preterm birth; developmental origins; causality
Rights: ©Copyright Oxford University Press, 2015
DOI: 10.1093/acprof:oso/9780199231034.003.0016
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