Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/70545
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dc.contributor.authorAdler, Christina Janeen
dc.contributor.authorThe Genographic Consortiumen
dc.date.issued2011en
dc.identifier.citationEuropean Journal of Human Genetics, 2011; 19(3):334-340en
dc.identifier.issn1018-4813en
dc.identifier.urihttp://hdl.handle.net/2440/70545-
dc.description.abstractCultural expansions, including of religions, frequently leave genetic traces of differentiation and in-migration. These expansions may be driven by complex doctrinal differentiation, together with major population migrations and gene flow. The aim of this study was to explore the genetic signature of the establishment of religious communities in a region where some of the most influential religions originated, using the Y chromosome as an informative male-lineage marker. A total of 3139 samples were analyzed, including 647 Lebanese and Iranian samples newly genotyped for 28 binary markers and 19 short tandem repeats on the non-recombinant segment of the Y chromosome. Genetic organization was identified by geography and religion across Lebanon in the context of surrounding populations important in the expansions of the major sects of Lebanon, including Italy, Turkey, the Balkans, Syria, and Iran by employing principal component analysis, multidimensional scaling, and AMOVA. Timing of population differentiations was estimated using BATWING, in comparison with dates of historical religious events to determine if these differentiations could be caused by religious conversion, or rather, whether religious conversion was facilitated within already differentiated populations. Our analysis shows that the great religions in Lebanon were adopted within already distinguishable communities. Once religious affiliations were established, subsequent genetic signatures of the older differentiations were reinforced. Post-establishment differentiations are most plausibly explained by migrations of peoples seeking refuge to avoid the turmoil of major historical events.en
dc.description.statementofresponsibilityMarc Haber, Daniel E Platt, Danielle A Badro, Yali Xue, Mirvat El-Sibai, Maziar Ashrafian Bonab, Sonia C Youhanna, Stephanie Saade, David F Soria-Hernanz, Ajay Royyuru, R Spencer Wells, Chris Tyler-Smith, Pierre A Zalloua and The Genographic Consortiumen
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.rights© 2011 Macmillan Publishers Limited. All rights reserved.en
dc.subjectY-chromosome; population genetics; human migrations; cultural diffusion; religion; Maronitesen
dc.titleInfluences of history, geography, and religion on genetic structure: the Maronites in Lebanonen
dc.typeJournal articleen
dc.contributor.schoolSchool of Earth and Environmental Sciencesen
dc.identifier.doi10.1038/ejhg.2010.177en
Appears in Collections:Earth and Environmental Sciences publications
Environment Institute publications

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