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Type: Journal article
Title: Comparative study on 1D (VP1) region of foot and mouth disease virus (Type A strain) among different isolates: Khorasan Razavi isolate and other Iranian and neighboring countries isolates
Author: Zibaei, S.
Keivanfar, H.
Rabbani, M.
Hemmatzadeh, F.
Kianizade, M.
Fathi najafi, M.
Farhodi, M.
Hemmati, M.
Citation: Journal of Veterinary Research, 2010; 65(3):199-202
Publisher: University of Tehran
Issue Date: 2010
ISSN: 2008-2525
Statement of
Saied Zibaei, Hadi Keivanfar, Mohammad Rabbani, Farhid Hematzadeh, Mehdi Kianizade, Mohsen Fathi najafi, Majid Farhodi and Mohammad Hemmati
Abstract: Foot-and-mouth disease (FMD) is one of the most important virus disease in farm animals. Types O, A and Asia1 FMD virus have been endemic in Iran. In these study, samples from suspected livestock were analyzed by RT-PCR experiment. The number of 702 nucleotides determined at 1D -2B region of type A strain isolated from Khorasan Razavi province sequenced and compared with that of other reported isolates type A from Iran and neighboring countries.The results show that field isolated type A has about 89% similarity with other reported isolates type A from Iran and neighboring countries. Furthermore, this virus shows the most similarity with A/IRN/1/87(Samuel). Phylogenitic analysis revealed that virus was closely related to A22-Iraq/99 and A/IRN/iso/105 that rest in the same lineage. The data showed high similarity between type A viruses involved in the Khorasan Razavi province and A/IRN/87v (vaccine strain); so that it can be concluded that the vaccine can produce prophylactic antibody against this virus.
Keywords: Type A; Foot and Mouth Disease Virus; Khorasan- Razavi Province
Rights: © All rights reserved. University of Tehran
RMID: 0020107448
Appears in Collections:Animal and Veterinary Sciences publications

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