Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/71706
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Type: | Journal article |
Title: | Timing of colonization of caries-producing bacteria: an approach based on studying monozygotic twin pairs |
Author: | Bockmann, M. White, A. Bennett, C. Odeh, R. Hughes, T. Townsend, G. |
Citation: | International Journal of Dentistry, 2011; 2011(571573):1-7 |
Publisher: | Hindawi Publishing Corporation |
Issue Date: | 2011 |
ISSN: | 1687-8728 1687-8736 |
Statement of Responsibility: | Michelle R. Bockmann, Abbe V. Harris, Corinna N. Bennett, Ruba Odeh, Toby E. Hughes and Grant C. Townsend |
Abstract: | Findings are presented from a prospective cohort study of timing of primary tooth emergence and timing of oral colonization of Streptococcus mutans (S. mutans) in Australian twins. The paper focuses on differences in colonization timing in genetically identical monozygotic (MZ) twins. Timing of tooth emergence was based on parental report. Colonization timing of S. Mutans were established by plating samples of plaque and saliva on selectivemedia at 3monthly intervals and assessing colony morphology. In 25% of individuals colonization occurred prior to emergence of the first tooth. A significant proportion ofMZ pairs (21%) was discordant for colonization occurring before or after first tooth emergence, suggesting a role of environmental or epigenetic factors in timing of tooth emergence, colonization by S. mutans, or both. These findings and further application of theMZ co-twin model should assist in development of strategies to prevent or delay infection with S. mutans in children. |
Description: | Extent: 7p. |
Rights: | Copyright © 2011 Michelle R. Bockmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
DOI: | 10.1155/2011/571573 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/565520 http://purl.org/au-research/grants/nhmrc/1006294 http://purl.org/au-research/grants/nhmrc/349448 |
Published version: | http://dx.doi.org/10.1155/2011/571573 |
Appears in Collections: | Aurora harvest Dentistry publications |
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hdl_71706.pdf | Published version | 518.48 kB | Adobe PDF | View/Open |
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