Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/71812
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Type: Journal article
Title: Follicle structure influences the availability of oxygen to the oocyte in antral follicles
Author: Clark, A.
Stokes, Y.
Citation: Computational and Mathematical Methods in Medicine, 2011; 2011(287186):1-9
Publisher: Hindawi Publishing Corporation
Issue Date: 2011
ISSN: 1748-670X
1748-6718
Statement of
Responsibility: 
A. R. Clark and Y. M. Stokes
Abstract: The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine follicles to the concentration in the immediate vicinity of the cumulus-oocyte complex (COC). The model predicts that the oxygen levels within the antral follicle are dependent on the size and structure of the follicle and that the mean level of dissolved oxygen in follicular fluid does not necessarily correspond to that reaching the COC.
Keywords: Ovarian Follicle; Follicular Fluid; Oocytes; Animals; Cattle; Oxygen; Models, Biological; Numerical Analysis, Computer-Assisted; Female
Rights: Copyright © 2011 A. R. Clark and Y. M. Stokes. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
RMID: 0020117553
DOI: 10.1155/2011/287186
Appears in Collections:Mathematical Sciences publications

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