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Type: Journal article
Title: Development in children with achondroplasia: a prospective clinical cohort study
Author: Ireland, P.
Donaghey, S.
McGill, J.
Zankl, A.
Ware, R.
Pacey, V.
Ault, J.
Savarirayan, R.
Sillence, D.
Thompson, E.
Townshend, S.
Johnston, L.
Citation: Developmental Medicine and Child Neurology, 2012; 54(6):532-537
Publisher: Cambridge Univ Press
Issue Date: 2012
ISSN: 0012-1622
Statement of
Penelope J. Ireland, Samantha Donaghey, James McGill, Andreas Zankl, Robert S. Ware, Verity Pacey, Jenny Ault, Ravi Savarirayan, David Sillence, Elizabeth Thompson, Sharron Townshend and Leanne M. Johnston
Abstract: AIM: Achondroplasia is characterized by delays in the development of communication andmotor skills. While previously reported developmental profiles exist across gross motor, fine motor, feeding, and communication skills, there has been no prospective study of development across multiple areas simultaneously. METHOD: This Australasian population-based study utilized a prospective questionnaire to quantify developmental data for skills in children born from 2000 to 2009. Forty-eight families from Australia and New Zealand were asked to report every 3 months on their child’s attainment of 41 milestones. Results include reference to previously available prospective information. RESULTS: Information from questionnaires was used to develop an achondroplasia-specific developmental recording form. The 25th, 50th, 75th, and 90th centiles were plotted to offer clear guidelines for development across gross motor, finemotor, feeding, and communication skills in children with achondroplasia. INTERPRETATIONS: Consistent with results from previous research, children with achondroplasia are delayed in development of gross motor and ambulatory skills. Young children with achondroplasia demonstrate a number of uniquemovement strategies that appear compensatory for the biomechanical changes.While delays were seen in development of later communication items, there were fewer delays seen across development of early communication, finemotor, and feeding skills.
Keywords: Humans
Disability Evaluation
Severity of Illness Index
Retrospective Studies
Cohort Studies
Developmental Disabilities
Child, Preschool
Family Health
Community Health Planning
New Zealand
Surveys and Questionnaires
Rights: © The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press
DOI: 10.1111/j.1469-8749.2012.04234.x
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Appears in Collections:Aurora harvest 5
Paediatrics publications

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