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Type: Journal article
Title: The effect of the GABAB receptor agonist baclofen on liquid and solid gastric emptying in mice
Author: Symonds, E.
Butler, R.
Omari, T.
Citation: Behavioural Processes, 2003; 470(1-2):95-97
Publisher: Elsevier Science BV
Issue Date: 2003
ISSN: 0014-2999
Abstract: The effect of the GABA(B) receptor agonist baclofen, a potential treatment for gastroesophageal reflux, on gastric emptying has not been determined. The effect of 1-4 mg/kg baclofen on liquid and solid gastric emptying in mice was evaluated by noninvasive [13C] breath tests. Baclofen accelerated gastric emptying of solids but delayed emptying of liquid, suggesting that it may have differential effects on proximal and distal stomach emptying.
Keywords: Animals
Mice, Inbred C57BL
Receptors, GABA-B
GABA Agonists
Gastric Emptying
GABA-B Receptor Agonists
DOI: 10.1016/S0014-2999(03)01779-5
Appears in Collections:Aurora harvest
Paediatrics publications

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