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dc.contributor.authorChang, J.en
dc.contributor.authorRusso, A.en
dc.contributor.authorBound, M.en
dc.contributor.authorRayner, C.en
dc.contributor.authorJones, K.en
dc.contributor.authorHorowitz, M.en
dc.identifier.citationDiabetes Care, 2012; 2012(12):1-3en
dc.description.abstractOBJECTIVE: To evaluate the natural history of gastric emptying in diabetes. RESEARCH DESIGN AND METHODS: Thirteen patients with diabetes (12, type 1; 1, type 2) had measurements of gastric emptying, blood glucose levels, glycated hemoglobin, upper gastrointestinal symptoms, and autonomic nerve function at baseline and after 24.7 ± 1.5 years. RESULTS: There was no change in gastric emptying of either solids (% retention at 100 min) (baseline 58.5 ± 5% vs. follow-up 51.9 ± 8%; P = 0.35) or liquids (50% emptying time) (baseline 29.8 ± 3 min vs. follow-up 34.3 ± 6 min; P = 0.37). Gastric emptying of solid at follow-up was related to emptying at baseline (r = 0.56, P < 0.05). At follow-up, blood glucose concentrations were lower (P = 0.006), autonomic function deteriorated (P = 0.03), and gastrointestinal symptoms remained unchanged (P = 0.17). CONCLUSIONS: In unselected patients with diabetes, gastric emptying appears remarkably stable over 25 years.en
dc.description.statementofresponsibilityJessica Chang, Antonietta Russo, Michelle Bound, Christopher K. Rayner, Karen L. Jones and Michael Horowitzen
dc.publisherAmer Diabetes Assocen
dc.rights© 2012 by the American Diabetes Associationen
dc.subjectHumans; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hemoglobin A, Glycosylated; Longitudinal Studies; Gastric Emptying; Aged; Middle Aged; Female; Maleen
dc.titleA 25-year longitudinal evaluation of gastric emptying in diabetesen
dc.typeJournal articleen
pubs.library.collectionMedicine publicationsen
dc.identifier.orcidRayner, C. [0000-0002-5527-256X]en
dc.identifier.orcidJones, K. [0000-0002-1155-5816]en
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]en
Appears in Collections:Medicine publications

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