Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/73423
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dc.contributor.authorChang, J.-
dc.contributor.authorRusso, A.-
dc.contributor.authorBound, M.-
dc.contributor.authorRayner, C.-
dc.contributor.authorJones, K.-
dc.contributor.authorHorowitz, M.-
dc.date.issued2012-
dc.identifier.citationDiabetes Care, 2012; 2012(12):1-3-
dc.identifier.issn0149-5992-
dc.identifier.issn1935-5548-
dc.identifier.urihttp://hdl.handle.net/2440/73423-
dc.description.abstractOBJECTIVE: To evaluate the natural history of gastric emptying in diabetes. RESEARCH DESIGN AND METHODS: Thirteen patients with diabetes (12, type 1; 1, type 2) had measurements of gastric emptying, blood glucose levels, glycated hemoglobin, upper gastrointestinal symptoms, and autonomic nerve function at baseline and after 24.7 ± 1.5 years. RESULTS: There was no change in gastric emptying of either solids (% retention at 100 min) (baseline 58.5 ± 5% vs. follow-up 51.9 ± 8%; P = 0.35) or liquids (50% emptying time) (baseline 29.8 ± 3 min vs. follow-up 34.3 ± 6 min; P = 0.37). Gastric emptying of solid at follow-up was related to emptying at baseline (r = 0.56, P < 0.05). At follow-up, blood glucose concentrations were lower (P = 0.006), autonomic function deteriorated (P = 0.03), and gastrointestinal symptoms remained unchanged (P = 0.17). CONCLUSIONS: In unselected patients with diabetes, gastric emptying appears remarkably stable over 25 years.-
dc.description.statementofresponsibilityJessica Chang, Antonietta Russo, Michelle Bound, Christopher K. Rayner, Karen L. Jones and Michael Horowitz-
dc.language.isoen-
dc.publisherAmer Diabetes Assoc-
dc.rights© 2012 by the American Diabetes Association-
dc.source.urihttp://dx.doi.org/10.2337/dc12-0028-
dc.subjectHumans-
dc.subjectDiabetes Mellitus, Type 1-
dc.subjectDiabetes Mellitus, Type 2-
dc.subjectLongitudinal Studies-
dc.subjectGastric Emptying-
dc.subjectAged-
dc.subjectMiddle Aged-
dc.subjectFemale-
dc.subjectMale-
dc.subjectGlycated Hemoglobin-
dc.titleA 25-year longitudinal evaluation of gastric emptying in diabetes-
dc.typeJournal article-
dc.identifier.doi10.2337/dc12-0028-
pubs.publication-statusPublished-
dc.identifier.orcidBound, M. [0000-0003-0211-5832]-
dc.identifier.orcidRayner, C. [0000-0002-5527-256X]-
dc.identifier.orcidJones, K. [0000-0002-1155-5816]-
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]-
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