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Type: Book chapter
Title: Diabetic Gastroparesis
Author: Rayner, C.
Jones, K.
Horowitz, M.
Citation: Gastroparesis: Pathophysiology, Presentation and Treatment, 2012 / Parkman, H., McCallum, R. (ed./s), pp.177-190
Publisher: Springer
Publisher Place: New York
Issue Date: 2012
ISBN: 1607615517
Statement of
Christopher K. Rayner, Karen L. Jones and Michael Horowitz
Abstract: Gastric emptying is frequently disordered in patients with long-standing type 1 and type 2 diabetes mellitus. While patients with diabetes present with similar symptoms to those with idiopathic gastroparesis, the relationship between gastric emptying and glycemic control represents an important additional consideration in the diabetic group. Specifically, acute variations in the blood glucose concentration affect the rate of gastric emptying, while conversely, gastric emptying is a key determinant of postprandial blood glucose. This has implications both for how gastroparesis should be defined in patients with diabetes, and for its optimal management.
Keywords: Diabetes mellitus; Interstitial cells of Cajal; Nitric oxide; Heme oxygenase 1; Incretin Glucagon-like peptide 1; insulin; blood glucose concentration
Description: Also has ISBN 1607615525 ; 9781607615521
RMID: 0020119603
DOI: 10.1007/978-1-60761-552-1_16
Appears in Collections:Medicine publications

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