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https://hdl.handle.net/2440/7410
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Type: | Journal article |
Title: | Resistance development in community-acquired strains of methicillin-resistant Staphylococcus aureus: an in vitro study |
Author: | Munckhof, W. Kleinschmidt, S. Turnidge, J. |
Citation: | International Journal of Antimicrobial Agents, 2004; 24(6):605-608 |
Publisher: | Elsevier Science BV |
Issue Date: | 2004 |
ISSN: | 0924-8579 1872-7913 |
Abstract: | This study compares in vitro antimicrobial resistance development between strains of Staphylococcus aureus including newly described community-acquired methicillin-resistant strains (CA-MRSA). High-level resistance developed in all strains of S. aureus after exposure to rifampicin and gentamicin and in some strains after fusidic acid exposure, independent of methicillin resistance phenotype. Resistance did not develop after exposure to clindamycin, cotrimoxazole, ciprofloxacin, linezolid, or vancomycin. These results have important implications for therapy of CA-MRSA infections. |
Keywords: | Humans Staphylococcus aureus Staphylococcal Infections Community-Acquired Infections Rifampin Gentamicins Microbial Sensitivity Tests Prevalence Methicillin Resistance Drug Resistance, Multiple |
DOI: | 10.1016/j.ijantimicag.2004.08.009 |
Published version: | http://dx.doi.org/10.1016/j.ijantimicag.2004.08.009 |
Appears in Collections: | Aurora harvest 5 Paediatrics publications |
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