Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/7410
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Type: Journal article
Title: Resistance development in community-acquired strains of methicillin-resistant Staphylococcus aureus: an in vitro study
Author: Munckhof, W.
Kleinschmidt, S.
Turnidge, J.
Citation: International Journal of Antimicrobial Agents, 2004; 24(6):605-608
Publisher: Elsevier Science BV
Issue Date: 2004
ISSN: 0924-8579
1872-7913
Abstract: This study compares in vitro antimicrobial resistance development between strains of Staphylococcus aureus including newly described community-acquired methicillin-resistant strains (CA-MRSA). High-level resistance developed in all strains of S. aureus after exposure to rifampicin and gentamicin and in some strains after fusidic acid exposure, independent of methicillin resistance phenotype. Resistance did not develop after exposure to clindamycin, cotrimoxazole, ciprofloxacin, linezolid, or vancomycin. These results have important implications for therapy of CA-MRSA infections.
Keywords: Humans
Staphylococcus aureus
Staphylococcal Infections
Community-Acquired Infections
Rifampin
Gentamicins
Microbial Sensitivity Tests
Prevalence
Methicillin Resistance
Drug Resistance, Multiple
DOI: 10.1016/j.ijantimicag.2004.08.009
Published version: http://dx.doi.org/10.1016/j.ijantimicag.2004.08.009
Appears in Collections:Aurora harvest 5
Paediatrics publications

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