Please use this identifier to cite or link to this item:
Scopus Web of ScienceĀ® Altmetric
Type: Journal article
Title: Analysis of the breath hydrogen test for carbohydrate malabsorption: Validation of a pocket-sized breath test analysier
Author: Lee, W.
Davidson, G.
Moore, D.
Butler, R.
Citation: Journal of Paediatrics and Child Health, 2000; 36(4):340-342
Publisher: Blackwell Publishing Asia
Issue Date: 2000
ISSN: 1034-4810
Abstract: <h4>Objective</h4>To assess the validity and clinical application of a hand-held breath hydrogen (H2) analyzer (BreatH2, Europa Scientific, Crewe, UK).<h4>Methodology</h4>Breath samples of patients referred to the Gastroenterology Unit, Women's and Children's Hospital, North Adelaide, South Australia, for confirmation of the diagnosis of carbohydrate malabsorption were analysed with the Quintron microlyzer (Quintron Instrument Co., Milwaukee, USA) and the BreatH2 analyser, using the Quintron microlyzer as the gold standard.<h4>Results</h4>Twenty-nine breath H2 tests (BHT) were performed in 29 patients aged 2 months to 61 years. The sensitivity and specificity of the BreatH2 analyser in detecting a positive BHT using the Quintron microlyser as the gold standard were 0.90 and 0.95 with positive and negative predictive values of 0.90 and 0.95, respectively. There was one false positive and one false negative reading. Bland-Altman plots showed a high degree of agreement between the values obtained with two different methods.<h4>Conclusions</h4>The diagnosis of carbohydrate malabsorption, using a portable breath H2 analyser (BreatH2), achieved an acceptable degree of sensitivity and specificity, enabling it to be used where no alternative is available.
Keywords: Humans
Carbohydrate Metabolism, Inborn Errors
Breath Tests
Sensitivity and Specificity
Reproducibility of Results
Middle Aged
Child, Preschool
DOI: 10.1046/j.1440-1754.2000.00511.x
Appears in Collections:Aurora harvest
Paediatrics publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.