Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/7591
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Type: Journal article
Title: The role of lower esophageal sphincter function and dysmotility in gastroesophageal reflux in premature infants and in the first year of life
Author: Davidson, G.
Citation: Journal of Pediatric Gastroenterology and Nutrition, 2003; 37(Supplement 1):S17-S22
Publisher: Lippincott Williams & Wilkins
Issue Date: 2003
ISSN: 0277-2116
1536-4801
Abstract: Transient relaxations of the lower esophageal sphincter (tLESRs), but not delayed gastric emptying, are major mechanisms of gastroesophageal reflux in premature infants. These findings are similar to those seen in older children and adults with gastroesophageal reflux disease. Newer antireflux therapies should be developed that target the reduction of gastric acidity or reduction in the number of tLESRs.
Keywords: Esophagogastric Junction; Humans; Gastroesophageal Reflux; Infant, Premature, Diseases; Gastrointestinal Motility; Gastric Emptying; Muscle Relaxation; Infant; Infant, Newborn; Infant, Premature; Female; Male
RMID: 0020030977
DOI: 10.1097/00005176-200311001-00005
Appears in Collections:Paediatrics publications

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