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|Title:||The role of lower esophageal sphincter function and dysmotility in gastroesophageal reflux in premature infants and in the first year of life|
|Citation:||Journal of Pediatric Gastroenterology and Nutrition, 2003; 37(Supplement 1):S17-S22|
|Publisher:||Lippincott Williams & Wilkins|
|Abstract:||Transient relaxations of the lower esophageal sphincter (tLESRs), but not delayed gastric emptying, are major mechanisms of gastroesophageal reflux in premature infants. These findings are similar to those seen in older children and adults with gastroesophageal reflux disease. Newer antireflux therapies should be developed that target the reduction of gastric acidity or reduction in the number of tLESRs.|
|Keywords:||Esophagogastric Junction; Humans; Gastroesophageal Reflux; Infant, Premature, Diseases; Gastrointestinal Motility; Gastric Emptying; Muscle Relaxation; Infant; Infant, Newborn; Infant, Premature; Female; Male|
|Appears in Collections:||Paediatrics publications|
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