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Type: Journal article
Title: The role of lower esophageal sphincter function and dysmotility in gastroesophageal reflux in premature infants and in the first year of life
Author: Davidson, G.
Citation: Journal of Pediatric Gastroenterology and Nutrition, 2003; 37(Supplement 1):S17-S22
Publisher: Lippincott Williams & Wilkins
Issue Date: 2003
ISSN: 0277-2116
Abstract: Transient relaxations of the lower esophageal sphincter (tLESRs), but not delayed gastric emptying, are major mechanisms of gastroesophageal reflux in premature infants. These findings are similar to those seen in older children and adults with gastroesophageal reflux disease. Newer antireflux therapies should be developed that target the reduction of gastric acidity or reduction in the number of tLESRs.
Keywords: Esophagogastric Junction
Gastroesophageal Reflux
Infant, Premature, Diseases
Gastrointestinal Motility
Gastric Emptying
Muscle Relaxation
Infant, Newborn
Infant, Premature
DOI: 10.1097/00005176-200311001-00005
Appears in Collections:Aurora harvest 4
Paediatrics publications

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