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Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/76996
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dc.contributor.authorChiam, K.-
dc.contributor.authorRicciardelli, C.-
dc.contributor.authorBianco-Miotto, T.-
dc.date.issued2014-
dc.identifier.citationCancer Letters, 2014; 342(2):248-256-
dc.identifier.issn0304-3835-
dc.identifier.issn1872-7980-
dc.identifier.urihttp://hdl.handle.net/2440/76996-
dc.description.abstractEpigenome alterations are characteristic of nearly all human malignancies and include changes in DNA methylation, histone modifications and microRNAs (miRNAs). However, what induces these epigenetic alterations in cancer is largely unknown and their mechanistic role in prostate tumorigenesis is just beginning to be evaluated. Identification of the epigenetic modifications involved in the development and progression of prostate cancer will not only identify novel therapeutic targets but also prognostic and diagnostic markers. This review will focus on the use of epigenetic modifications as biomarkers for prostate cancer.-
dc.description.statementofresponsibilityKaren Chiam, Carmela Ricciardelli and Tina Bianco-Miotto-
dc.language.isoen-
dc.publisherElsevier Sci Ireland Ltd-
dc.rights© 2012 Elsevier Ireland Ltd. All rights reserved.-
dc.source.urihttp://dx.doi.org/10.1016/j.canlet.2012.02.011-
dc.subjectAnimals-
dc.subjectHumans-
dc.subjectProstatic Neoplasms-
dc.subjectGenetic Predisposition to Disease-
dc.subjectHistones-
dc.subjectMicroRNAs-
dc.subjectPrognosis-
dc.subjectPredictive Value of Tests-
dc.subjectDNA Methylation-
dc.subjectEpigenesis, Genetic-
dc.subjectGene Expression Regulation, Neoplastic-
dc.subjectPhenotype-
dc.subjectMale-
dc.subjectGenetic Testing-
dc.subjectBiomarkers, Tumor-
dc.titleEpigenetic biomarkers in prostate cancer: current and future uses-
dc.typeJournal article-
dc.identifier.doi10.1016/j.canlet.2012.02.011-
pubs.publication-statusPublished-
dc.identifier.orcidRicciardelli, C. [0000-0001-7415-1854]-
dc.identifier.orcidBianco-Miotto, T. [0000-0002-8431-5338]-
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Obstetrics and Gynaecology publications

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