Please use this identifier to cite or link to this item:
Full metadata record
|dc.identifier.citation||Journal of Health, Safety and Environment, 2011; 27(2):1-7||-|
|dc.description.abstract||Occupational exposure to antineoplastic agents can cause acute and chronic health effects from repeated dermal contact with contaminated surfaces in healthcare centres. Although relevant guidelines and standards recommend some specific cleaning reagents, information on the decontamination efficiency of the cleaning reagents is limited. The aim of this study was to examine the efficiency of six cleaning reagents (0.5% w/v sodium hypochloride, 0.03M sodium hydroxide, 70% isopropyl alcohol, 70% ethanol, acentonitrile, distilled water) against three antineoplastic agents (Fluorouracil, Cyclophosphamide and Paclitaxel)commonly used in South Australia. A decomposition test of three antineoplastic agents in each cleaning reagent was undertaken using a HPLC system under ambient temperature conditions at a number of time intervlas (1, 15, 30, 60, 80 minutes). This study found that 70% ethanol and isopropanol did not significantly degrade the three antineoplastic agents. Sodium hypochlorite (0.5% w/v chlorine based bleaching agent) was the most effective cleaning reagent to decontaminate the three antineoplastic agents.||-|
|dc.description.statementofresponsibility||Su-Gil Lee, Michael Tkaczuk, Ganyk Jankewicz and Dino Pisaniello||-|
|dc.publisher||CCH Australia Ltd||-|
|dc.title||A study of the efficiency of cleaning reagents for three antineoplastic agents (5-FU, CP, PT) commonly used in hospitals in South Australia||-|
|dc.identifier.orcid||Pisaniello, D. [0000-0002-4156-0608]||-|
|Appears in Collections:||Aurora harvest 4|
Public Health publications
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.