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Type: Journal article
Title: Nutritional approaches to breaking the intergenerational cycle of obesity
Author: Muhlhausler, B.
Gugusheff, J.
Ong, Z.
Vithayathil, M.
Citation: Canadian Journal of Physiology and Pharmacology, 2013; 91(6):421-428
Publisher: National Research Council Canada
Issue Date: 2013
ISSN: 0008-4212
Statement of
Beverly S. Muhlhausler, Jessica R. Gugusheff, Zhi Yi Ong and Mini A. Vithayathil
Abstract: The link between poor maternal nutrition and an increased burden of disease in subsequent generations has been widely demonstrated in both human and animal studies. Historically, the nutritional challenges experienced by pregnant and lactating women were largely those of insufficient calories and severe micronutrient deficiencies. More recently, however, Western societies have been confronted with a new nutritional challenge; that of maternal obesity and excessive maternal intake of calories, fat, and sugar. Exposure of the developing fetus and infant to this obesogenic environment results in an increased risk of obesity and metabolic disease later in life. Furthermore, increased caloric, fat, and sugar intake can occur in conjunction with micronutrient deficiency, which may further exacerbate these programming effects. In light of the current epidemic of obesity and metabolic disease, attention has now turned to identifying nutritional interventions for breaking this intergenerational obesity cycle. In this review, we discuss the approaches that have been explored to date and highlight the need for further research.
Keywords: Maternal nutrition
fetal programming
maternal obesity
Rights: © Copyright 2013 – Canadian Science Publishing
DOI: 10.1139/cjpp-2012-0353
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