Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/79402
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHughes, T.en
dc.contributor.authorBockmann, M.en
dc.contributor.authorMihailidis, S.en
dc.contributor.authorBennett, C.en
dc.contributor.authorHarris, A.en
dc.contributor.authorSeow, W.en
dc.contributor.authorLekkas, D.en
dc.contributor.authorRanjitkar, S.en
dc.contributor.authorRupinskas, L.en
dc.contributor.authorPinkerton, S.en
dc.contributor.authorBrook, A.en
dc.contributor.authorSmith, R.en
dc.contributor.authorTownsend, G.en
dc.date.issued2013en
dc.identifier.citationTwin Research and Human Genetics, 2013; 16(1):43-51en
dc.identifier.issn1832-4274en
dc.identifier.issn1839-2628en
dc.identifier.urihttp://hdl.handle.net/2440/79402-
dc.description.abstractThe Craniofacial Biology Research Group in the School of Dentistry at The University of Adelaide is entering an exciting new phase of its studies of dental development and oral health in twins and their families. Studies of the teeth and faces of Australian twins have been continuing for nearly 30 years, with three major cohorts of twins recruited over that time, and currently we are working with twins aged 2 years old to adults. Cross-sectional data and records relating to teeth and faces of twins are available for around 300 pairs of teenage twins, as well as longitudinal data for 300 pairs of twins examined at three different stages of development, once with primary teeth, once at the mixed dentition stage, and then again when the permanent teeth had emerged. The third cohort of twins comprises over 600 pairs of twins recruited at around birth, together with other family members. The emphasis in this third group of twins has been to record the timing of emergence of the primary teeth and also to sample saliva and dental plaque to establish the timing of colonization of decay-forming bacteria in the mouth. Analyses have confirmed that genetic factors strongly influence variation in timing of primary tooth emergence. The research team is now beginning to carry out clinical examinations of the twins to see whether those who become colonized earlier with decay-forming bacteria develop dental decay at an earlier age. By making comparisons within and between monozygotic (MZ) and dizygotic (DZ) twin pairs and applying modern molecular approaches, we are now teasing out how genetic, epigenetic, and environmental factors interact to influence dental development and also oral health.en
dc.description.statementofresponsibilityToby Hughes, Michelle Bockmann, Suzanna Mihailidis, Corinna Bennett, Abbe Harris, W. Kim Seow, Dimitra Lekkas, Sarbin Ranjitkar, Loreta Rupinskas, Sandra Pinkerton, Alan Brook, Richard Smith and Grant C. Townsenden
dc.language.isoenen
dc.publisherAustralian Academic Press Pty. Ltd.en
dc.rights© The Authors 2012en
dc.subjectteeth; faces; twins; dentistry; craniofacial developmenten
dc.titleGenetic, epigenetic, and environmental influences on dentofacial structures and oral health: Ongoing studies of australian twins and their familiesen
dc.typeJournal articleen
dc.identifier.rmid0020125622en
dc.identifier.doi10.1017/thg.2012.78en
dc.identifier.pubid21195-
pubs.library.collectionDentistry publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidHughes, T. [0000-0001-8668-7744]en
dc.identifier.orcidBockmann, M. [0000-0001-8050-0993]en
dc.identifier.orcidLekkas, D. [0000-0002-5142-7333]en
dc.identifier.orcidRanjitkar, S. [0000-0003-1957-0719]en
dc.identifier.orcidBrook, A. [0000-0002-3484-3888]en
Appears in Collections:Dentistry publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.