Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/79485
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Type: Journal article
Title: Differentiating disordered affect in children and adolescents with type 1 diabetes
Author: Sinnamon, G.
Caltabiano, M.
Baune, B.
Citation: Journal of Affective Disorders, 2013; 147(1-3):51-58
Publisher: Elsevier Science BV
Issue Date: 2013
ISSN: 0165-0327
1573-2517
Statement of
Responsibility: 
Grant C.B. Sinnamon, Marie Caltabiano and Bernhard T. Baune
Abstract: <h4>Background</h4>There is evidence for increased risk of affective disorders (AD) in adults with type 1 diabetes however, the prevalence and characteristics of AD in young people with the condition is unclear. Comorbid AD in type 1 diabetes is associated with deleterious self-management, sub-optimal clinical indicators, reduced quality of life, poorer physical health, increased complications, increased high risk behaviours in adolescence and young adulthood, and earlier mortality. The present study investigated the prevalence and character of AD in young people with type 1 diabetes.<h4>Methods</h4>The self-report PH-PANAS-C was employed in a cross-sectional, case-control design to identify and differentiate full-syndrome (FS) and subthreshold (St) levels of AD in 53 participants with type 1 diabetes (case) and 54 age-balanced controls (N=107; 7-18 yrs).<h4>Results</h4>Case participants reported greater AD than controls. When differentiated, only anxiety was significantly more prevalent. Case participants reported less positive affect, and greater negative affect and autonomic arousal. Further, 1:3 case participants presented with St symptoms of AD.<h4>Limitations</h4>Self-report measures are known to produce moderated responses therefore symptoms may be more severe than reported. There has been some suggestion that responses to somatic items in the PH-PANAS-C may relate to diabetes-specific states rather than affect-related symptoms however, recent evidence has refuted this argument.<h4>Conclusions</h4>AD, particularly anxiety, represents a significant clinical concern in young people with type 1 diabetes both as a disorder in its own right and as a major impediment to primary care and management of the diabetes. The significant dominance of anxiety-related symptoms and prevalence of subthreshold presentation warrant further investigation.
Keywords: Humans
Diabetes Mellitus, Type 1
Prevalence
Case-Control Studies
Cross-Sectional Studies
Anxiety Disorders
Mood Disorders
Comorbidity
Adolescent
Child
Female
Male
Self Report
Rights: © 2013 Elsevier B.V. All rights reserved.
DOI: 10.1016/j.jad.2012.10.006
Appears in Collections:Aurora harvest 4
Psychiatry publications

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